Breast cancer complicated by pleural effusion: Patient characteristics and results of surgical management

Simple item page
dc.contributor.authorApffelstaedt J.P.
dc.contributor.authorVan Zyl J.A.
dc.contributor.authorMuller A.G.S.
dc.date.accessioned2011-05-15T16:05:04Z
dc.date.available2011-05-15T16:05:04Z
dc.date.issued1995
dc.description.abstractTo evaluate the efficiency of pleurodesis (PD) in the management of symptomatic malignant pleural effusion (PE) in breast cancer, we reviewed 46 patients undergoing 49 PDs. When radiotherapy was part of the initial treatment, 41% of PEs were ipsilateral to the primary, if not, 85% of PEs were ipsilateral (P <0.0075). Six percent of patients presented dyspneic with exertion, 32% during daily routine; 61% at rest. All except 1 were improved after PD; 74% had no dyspnea, 23% had exertional dyspnea. PD relieved chest pain in 4 and cough in 5 patients. With 31 Talc/Iodine PDs, 2 mortalities and 2 minor complications occurred. Of 17 tetracycline PDs, 1 was complicated by bronchopleural fistula and 1 failed. 1 Mustine PD was uncomplicated. Survival at 6, 12, and 24 months was 58%, 40%, and 13%, respectively. Primary local radiotherapy may prevent ipsilateral PE. Talc/Iodine and tetracycline PD reliably provide relief from the distressing symptoms of malignant PE.
dc.description.versionArticle
dc.identifier.citationJournal of Surgical Oncology
dc.identifier.citation58
dc.identifier.citation3
dc.identifier.issn224790
dc.identifier.other10.1002/jso.2930580307
dc.identifier.urihttp://hdl.handle.net/10019.1/12959
dc.subjectalpha interferon
dc.subjectbeta interferon
dc.subjectbleomycin
dc.subjectchlormethine
dc.subjectdoxycycline
dc.subjectfibrin
dc.subjectiodine
dc.subjectmitoxantrone
dc.subjecttalc
dc.subjecttetracycline
dc.subjectarticle
dc.subjectbreast cancer
dc.subjectbronchopleural fistula
dc.subjectcancer radiotherapy
dc.subjectcancer survival
dc.subjectclinical article
dc.subjectclinical feature
dc.subjectclinical trial
dc.subjectcoughing
dc.subjectdyspnea
dc.subjectfemale
dc.subjecthuman
dc.subjectmale
dc.subjectpleura effusion
dc.subjectpleurodesis
dc.subjectpriority journal
dc.subjectPropionibacterium acnes
dc.subjectsurgical drainage
dc.subjectthorax pain
dc.subjecttreatment failure
dc.subjectBreast Neoplasms
dc.subjectBreast Neoplasms, Male
dc.subjectCombined Modality Therapy
dc.subjectFemale
dc.subjectHuman
dc.subjectIodine
dc.subjectMale
dc.subjectMastectomy
dc.subjectNeoplasm Staging
dc.subjectPleural Effusion, Malignant
dc.subjectPleurodesis
dc.subjectSurvival Rate
dc.subjectTalc
dc.subjectTreatment Outcome
dc.titleBreast cancer complicated by pleural effusion: Patient characteristics and results of surgical management
dc.typeArticle
Files
Collections
Stellenbosch University - Scopus Publications