Retrospective analysis of radiotherapy outcomes in breast cancer radiotherapy at a single institution
dc.contributor.author | Heunis, M. | en_ZA |
dc.contributor.author | Lombe, D. C. | en_ZA |
dc.contributor.author | McCaulb, M. | en_ZA |
dc.date.accessioned | 2020-02-10T09:27:01Z | |
dc.date.available | 2020-02-10T09:27:01Z | |
dc.date.issued | 2018 | |
dc.description | CITATION: Heunis, M., Lombe, D. C. & McCaulb, M. 2018. Retrospective analysis of radiotherapy outcomes in breast cancer radiotherapy at a single institution. Southern African Journal of Gynaecological Oncology, 10(1):1-4, doi:10.1080/20742835.2018.1429521. | |
dc.description | The original publication is available at https://www.tandfonline.com | |
dc.description.abstract | Introduction: Breast cancer is the most commonly diagnosed cancer worldwide. With the challenges of cancer treatment in developing countries there is a need for a systematic and methodical approach to treatment in resource-limited settings. Objective: To retrospectively evaluate the profile of breast cancer patients irradiated with curative intent and discuss the therapeutic outcomes, and to compare this cohort with the available developed-world data. Methods: A retrospective cohort of 689 breast cancer patients from 2010–2014 at Tygerberg Hospital, Western Cape Province was analysed. The best-case disease-free survival was calculated at five years and compared with the SEER database. Various prognostic factors were calculated by univariate and multivariate analysis. Results: The five-year best-case disease-free survival (DFS) for Stage I is 94.7% (95% CI 68–99) and for Stage IIIC, 71.3% (95% CI 39–88). Conclusion: Outcomes of treatment at this institution are comparable to data reported in first-world countries. As twodimensional radiotherapy compares with most Cobalt specifications, the majority of breast cancer patients in sub-Saharan Africa can be treated efficiently with Cobalt-type technology. | en_ZA |
dc.description.uri | https://www.tandfonline.com/doi/full/10.1080/20742835.2018.1429521 | |
dc.description.version | Publisher's version | |
dc.format.extent | 4 pages ; illustrations | |
dc.identifier.citation | Heunis, M., Lombe, D. C. & McCaulb, M. 2018. Retrospective analysis of radiotherapy outcomes in breast cancer radiotherapy at a single institution. Southern African Journal of Gynaecological Oncology, 10(1):1-4, doi:10.1080/20742835.2018.1429521 | |
dc.identifier.issn | 2220-105X (online) | |
dc.identifier.issn | 2074-2835 (print) | |
dc.identifier.other | doi:10.1080/20742835.2018.1429521 | |
dc.identifier.uri | http://hdl.handle.net/10019.1/107459 | |
dc.language.iso | en_ZA | en_ZA |
dc.publisher | Medpharm Publications | |
dc.rights.holder | Authors retain copyright | |
dc.subject | Breast -- Cancer -- Patients | en_ZA |
dc.subject | Breast -- Cancer -- Radiotherapy | en_ZA |
dc.title | Retrospective analysis of radiotherapy outcomes in breast cancer radiotherapy at a single institution | en_ZA |
dc.type | Article | en_ZA |