Tioconazole in the treatment of vaginal candidosis

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dc.contributor.authorSchaetzing A.
dc.date.accessioned2011-05-15T16:17:25Z
dc.date.available2011-05-15T16:17:25Z
dc.date.issued1988
dc.description.abstractA 3-day treatment with tioconazole vaginal tablets (Gyno-Trosid; Pfizer) was used in 30 patients with vaginal candidosis during a prospective, mycologically controlled study. Candida yeasts were identified by microscopy and culture before initiation of treatment and then on days 3, 6 and 28. On the 6th day, all patients had responded to the treatment and there was a 100% cure rate on microscopic and mycological examination. After 4 weeks, 83% of the patients still had relief of symptoms, although a recurrence of Candida on culture and microscopy was detected in 14 patients (46%). Seven of these were available for further assessment and, when given a second course of treatment, they were cured both clinically and microbiologically. There was no evidence of any adverse systemic reaction and local side effects were limited to a transient sensation of mild to moderate burning. Problems relating to recurrence of symptoms and reappearance of Candida are discussed.
dc.description.versionArticle
dc.identifier.citationMycoses
dc.identifier.citation31
dc.identifier.citation11
dc.identifier.issn09337407
dc.identifier.urihttp://hdl.handle.net/10019.1/14208
dc.subjecttioconazole
dc.subjecttopical agent
dc.subjectadult
dc.subjectautopsy
dc.subjectcandida albicans
dc.subjectclinical article
dc.subjectetiology
dc.subjectfemale
dc.subjectfungus
dc.subjectnonhuman
dc.subjectreinfection
dc.subjectrelapse
dc.subjecttopical drug administration
dc.subjectultrastructure
dc.subjectvagina candidiasis
dc.subjectAdult
dc.subjectAntifungal Agents
dc.subjectCandidiasis, Vulvovaginal
dc.subjectFemale
dc.subjectHuman
dc.subjectImidazoles
dc.subjectMiddle Age
dc.subjectProspective Studies
dc.titleTioconazole in the treatment of vaginal candidosis
dc.typeArticle
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