Cyclic AMP increase the Na+ permeability of the avian erythrocyte membrane by a process which does not involve protein phosphorylation

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dc.contributor.authorWeller M.
dc.contributor.authorLaing W.
dc.date.accessioned2011-05-15T16:00:02Z
dc.date.available2011-05-15T16:00:02Z
dc.date.issued1978
dc.description.abstractPreparations of avian erythrocyte plasma membranes have been made which are in the form of sealed vesicles. Using these preparations the permeability of the membranes to Na+, K+, Mg2+ and Ca2+ was measured. Monobutyryl cyclic AMP and cyclic AMP increased the permeability to Na+ and Ca+ under conditions where no protein phosphorylation could occur. The only effect of phosphorylation of membrane proteins was to reduce Ca+ permeability. It is thus concluded that cyclic AMP increases Na+ permeability in the avian erythrocyte by a direct effect which does not involve protein phosphorylation.
dc.description.versionArticle
dc.identifier.citationMolecular and Cellular Biochemistry
dc.identifier.citation20
dc.identifier.citation2
dc.identifier.issn3008177
dc.identifier.urihttp://hdl.handle.net/10019.1/11493
dc.subjectcalcium
dc.subjectcyclic amp
dc.subjectmagnesium
dc.subjectpotassium
dc.subjectprotein kinase
dc.subjectsodium
dc.subjectanimal experiment
dc.subjectblood and hemopoietic system
dc.subjectchicken
dc.subjecterythrocyte membrane
dc.subjectAnimal
dc.subjectCalcium
dc.subjectCell Membrane Permeability
dc.subjectChickens
dc.subjectCyclic AMP
dc.subjectErythrocyte Membrane
dc.subjectErythrocytes
dc.subjectMagnesium
dc.subjectMembrane Proteins
dc.subjectPotassium
dc.subjectSodium
dc.titleCyclic AMP increase the Na+ permeability of the avian erythrocyte membrane by a process which does not involve protein phosphorylation
dc.typeArticle
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