Autosome and sex chromosome diversity among the African pygmy mice, subgenus Nannomys (Murinae; Mus)

Simple item page
dc.contributor.authorVeyrunes F.
dc.contributor.authorCatalan J.
dc.contributor.authorSicard B.
dc.contributor.authorRobinson T.J.
dc.contributor.authorDuplantier J.-M.
dc.contributor.authorGranjon L.
dc.contributor.authorDobigny G.
dc.contributor.authorBritton-Davidian J.
dc.date.accessioned2011-05-15T15:59:04Z
dc.date.available2011-05-15T15:59:04Z
dc.date.issued2004
dc.description.abstractThe African pygmy mice, subgenus Nannomys, constitute the most speciose lineage of the genus Mus with 19 recognized species. Although morphologically very similar, they exhibit considerable chromosomal diversity which is here confirmed and extended by the G-banding analysis of 65 mice from West and South Africa. On the basis of their karyotype and distribution area, the specimens were assigned to at least five species. Extensive differentiation both within and between species was observed that involved almost exclusively Robertsonian translocations, 23 of which are newly described. Two of the rearrangements were sex chromosome-autosome translocations, associated in some cases with partial deletions of the X or Y chromosomes. Several authors have predicted that the highly deleterious effect of this rearrangement would be reduced if the sex and autosomal segments were insulated by a block of centromeric heterochromatin. The C-banding analyses performed showed that among the species carrying X-autosome translocations, one followed the expected pattern, while the other did not. In this case, functional isolation of the sex and autosome compartments must involve other repetitive sequences or genomic traits that require further molecular characterization. Such studies will provide insight into the causes and consequences of the high diversity of sex chromosome rearrangements in this subgenus.
dc.description.versionArticle
dc.identifier.citationChromosome Research
dc.identifier.citation12
dc.identifier.citation4
dc.identifier.issn9673849
dc.identifier.other10.1023/B:CHRO.0000034098.09885.e6
dc.identifier.urihttp://hdl.handle.net/10019.1/10990
dc.publisherKLUWER
dc.subjectarticle
dc.subjectautosome
dc.subjectbiodiversity
dc.subjectC banding
dc.subjectcentromere
dc.subjectchromosome deletion
dc.subjectchromosome G band
dc.subjectchromosome high resolution banding analysis
dc.subjectchromosome translocation
dc.subjectcontrolled study
dc.subjectcytogenetics
dc.subjectgene rearrangement
dc.subjectgenetic trait
dc.subjectgenetic variability
dc.subjectheterochromatin
dc.subjectkaryotype
dc.subjectmolecular recognition
dc.subjectmouse strain
dc.subjectnonhuman
dc.subjectprediction
dc.subjectpriority journal
dc.subjectRobertsonian chromosome translocation
dc.subjectsex chromosome
dc.subjectAfrica South of the Sahara
dc.subjectAnimals
dc.subjectChromosome Banding
dc.subjectKaryotyping
dc.subjectMuridae
dc.subjectSex Chromosomes
dc.subjectSpecies Specificity
dc.subjectTranslocation, Genetic
dc.subjectBaiomys
dc.subjectMurinae
dc.subjectMus
dc.subjectRobertsonia
dc.subjectRodentia
dc.titleAutosome and sex chromosome diversity among the African pygmy mice, subgenus Nannomys (Murinae; Mus)
dc.typeArticle
Files
Collections
Stellenbosch University - Scopus Publications