The Role of the Sympathetic Nervous System in the Long QT Syndrome: The Long Road from Pathophysiology to Therapy

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dc.contributor.authorSchwartz P.J.
dc.date.accessioned2012-04-12T08:19:48Z
dc.date.available2012-04-12T08:19:48Z
dc.date.issued2012
dc.description.abstractThis article reviews the role of the sympathetic nervous system in long QT syndrome (LQTS), in light of clinical and personal experience. The evolution of concepts related to LQTS is examined after 40 years of research and treatment. Studies stimulated by the sympathetic imbalance hypothesis have generated many unsuspected novel data and have provided an extremely strong rationale for the therapeutic use of left cardiac sympathetic denervation to prevent ventricular fibrillation, not only in LQTS but also in other life-threatening diseases associated with high risk for arrhythmic sudden death. © 2012 Elsevier Inc.
dc.identifier.citationCardiac Electrophysiology Clinics
dc.identifier.citation4
dc.identifier.citation1
dc.identifier.citation75
dc.identifier.citation85
dc.identifier.issn18779182
dc.identifier.other10.1016/j.ccep.2012.01.002
dc.identifier.urihttp://hdl.handle.net/10019.1/20551
dc.subjectArrhythmic sudden death
dc.subjectLeft cardiac sympathetic denervation
dc.subjectLong QT syndrome
dc.subjectSympathetic imbalance
dc.titleThe Role of the Sympathetic Nervous System in the Long QT Syndrome: The Long Road from Pathophysiology to Therapy
dc.typeReview
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