A paradox revealed: Karyotype evolution in the four-horned antelope occurs by tandem fusion (Mammalia, Bovidae, Tetracerus quadricornis)

Simple item page
dc.contributor.authorRopiquet A.
dc.contributor.authorHassanin A.
dc.contributor.authorPagacova E.
dc.contributor.authorGerbault-Seureau M.
dc.contributor.authorCernohorska H.
dc.contributor.authorKubickova S.
dc.contributor.authorBonillo C.
dc.contributor.authorRubes J.
dc.contributor.authorRobinson T.J.
dc.date.accessioned2011-05-15T15:59:03Z
dc.date.available2011-05-15T15:59:03Z
dc.date.issued2010
dc.description.abstractThe four-horned antelope, Tetracerus quadricornis, is a karyotypic novelty in Bovidae since chromosomal evolution in this species is driven by tandem fusions in contradiction to the overwhelming influence of Robertsonian fusions in other species within the family. Using a combination of differential staining and molecular cytogenetic techniques, we provide the first description of the species' karyotype, draw phylogenetic inferences from the cytogenetic data and discuss possible mechanisms underlying the formation of the tandem fusions in this species. We show (a) that pairs 1-6 of Tetracerus correspond to a combination of Bos taurus orthologous chromosomes that are tandemly fused head to tail, (b) the presence of interstitial centromeric satellite DNA at the junctions of orthologous blocks defined by the crossspecies painting data and (c) that in some instances, residual telomeric sequences persist at these sites. We conclude that the attendant result of each fusion is an enlarged acrocentric fusion element comprising a single functional centromere and two terminal telomeres that, collectively, led to a reduction of the 2n=58 bovid ancestral acrocentric chromosomal complement to the 2n=38 detected in the four-horned antelope.
dc.description.versionArticle
dc.identifier.citationChromosome Research
dc.identifier.citation18
dc.identifier.citation2
dc.identifier.issn9673849
dc.identifier.other10.1007/s10577-010-9115-1
dc.identifier.urihttp://hdl.handle.net/10019.1/10975
dc.subjectantelope
dc.subjectarticle
dc.subjectC banding
dc.subjectcentromere
dc.subjectchromosome painting
dc.subjectcytogenetics
dc.subjectfluorescence in situ hybridization
dc.subjectgenetic transformation
dc.subjectkaryotype evolution
dc.subjectmolecular evolution
dc.subjectnonhuman
dc.subjectphylogeny
dc.subjectpriority journal
dc.subjecttelomere
dc.subjectTetracerus quadricornis
dc.subjectAnimals
dc.subjectAntelopes
dc.subjectCentromere
dc.subjectChromosomes, Mammalian
dc.subjectEvolution
dc.subjectKaryotyping
dc.subjectPhylogeny
dc.subjectSynteny
dc.subjectTelomere
dc.subjectBos taurus
dc.subjectBovidae
dc.subjectMammalia
dc.subjectRobertsonia
dc.subjectTetracerus
dc.subjectTetracerus quadricornis
dc.titleA paradox revealed: Karyotype evolution in the four-horned antelope occurs by tandem fusion (Mammalia, Bovidae, Tetracerus quadricornis)
dc.typeArticle
Files
Collections
Stellenbosch University - Scopus Publications