Gestational trophoblastic neoplasm and women living with HIV and/or AIDS
Date
2015-07-03
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
AOSIS Publishing
Abstract
The 2011 World Health Organization global report on HIV and/or AIDS estimated that sub-Saharan Africa comprised 67% of the global HIV burden, with a current estimate of 5.9 million cases in South Africa. Since the introduction of antiretroviral therapy,
there has been an increase in the incidence of non-AIDS-defining cancers. Gestational trophoblastic neoplasm (GTN) is a rare pregnancy-related disorder with an incidence ranging from 0.12–0.7/1000 pregnancies in Western nations. The overall cure rate is about 90%. Response to treatment for GTN is generally favourable; but the sequelae of HIV and/or AIDS, the resultant low CD4 counts, comorbidities, poor performance status and the extent of metastatic disease in patients receiving chemotherapy, compromise the
prognosis and survival.
Description
CITATION: Barnardt, P. & Relling, M. 2015. Gestational trophoblastic neoplasm and women living with HIV and/or AIDS. Southern African Journal of HIV Medicine, 16(1), Art.
#344, doi:10.4102/sajhivmed.v16i1.344.
The original publication is available at http://www.sajhivmed.org.za
The original publication is available at http://www.sajhivmed.org.za
Keywords
Gestational trophoblastic neoplasm, HIV-positive women -- South Africa, Gestational trophoblastic disease -- South Africa, HIV (Viruses) -- Risk factors -- South Africa
Citation
Barnardt, P. & Relling, M. 2015. Gestational trophoblastic neoplasm and women living with HIV and/or AIDS. Southern African Journal of HIV Medicine, 16(1), Art.
#344, doi:10.4102/sajhivmed.v16i1.344.