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Gestational trophoblastic neoplasm and women living with HIV and/or AIDS

Barnardt, Pieter ; Relling, Martha (2015-07-03)

CITATION: Barnardt, P. & Relling, M. 2015. Gestational trophoblastic neoplasm and women living with HIV and/or AIDS. Southern African Journal of HIV Medicine, 16(1), Art. #344, doi:10.4102/sajhivmed.v16i1.344.

The original publication is available at http://www.sajhivmed.org.za

Article

The 2011 World Health Organization global report on HIV and/or AIDS estimated that sub-Saharan Africa comprised 67% of the global HIV burden, with a current estimate of 5.9 million cases in South Africa. Since the introduction of antiretroviral therapy, there has been an increase in the incidence of non-AIDS-defining cancers. Gestational trophoblastic neoplasm (GTN) is a rare pregnancy-related disorder with an incidence ranging from 0.12–0.7/1000 pregnancies in Western nations. The overall cure rate is about 90%. Response to treatment for GTN is generally favourable; but the sequelae of HIV and/or AIDS, the resultant low CD4 counts, comorbidities, poor performance status and the extent of metastatic disease in patients receiving chemotherapy, compromise the prognosis and survival.

Please refer to this item in SUNScholar by using the following persistent URL: http://hdl.handle.net/10019.1/99414
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