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Diagnostic yield of fine needle aspiration biopsy in HIV-infected adults with suspected mycobacterial lymphadenitis

dc.contributor.authorRazack, R.en_ZA
dc.contributor.authorLouw, M.en_ZA
dc.contributor.authorWright, C. A.en_ZA
dc.date.accessioned2015-11-25T12:14:46Z
dc.date.available2015-11-25T12:14:46Z
dc.date.issued2014-01
dc.identifier.citationRazack, R., Louw, M. & Wright, C. A. 2014. Diagnostic yield of fine needle aspiration biopsy in HIV-infected adults with suspected mycobacterial lymphadenitis. South African Medical Journal 104(1):27-28. DOI:10.7196/SAMJ.7492.en_ZA
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.otherdoi:10.7196/SAMJ.7492
dc.identifier.urihttp://hdl.handle.net/10019.1/97648
dc.descriptionPlease cite as follows: Razack, R., Louw, M. & Wright, C. A. 2014. Diagnostic yield of fine needle aspiration biopsy in HIV-infected adults with suspected mycobacterial lymphadenitis. South African Medical Journal 104(1):27-28. DOI:10.7196/SAMJ.7492.en_ZA
dc.descriptionThe original publication is available at http://www.samj.org.zaen_ZA
dc.description.abstractBackground: Fine needle aspiration biopsy (FNAB) has been shown to be the diagnostic procedure of choice for superficial lymphadenitis in tuberculosis endemic regions. Methods: We conducted a retrospective laboratory-based study to determine the bacteriological yield of clinically suspected mycobacterial tuberculous lymphadenitis following FNAB in adults, and specifically HIV-positive patients, to determine the need for the introduction of automated nucleic acid amplification tests (NAATs) such as the Xpert MTB/RIF assay as the initial diagnostic modality. Results: A diagnostic yield of 80% was achieved, significantly higher in HIV-positive v. HIV-negative patients (84% v. 52%, respectively; p<0.001). Conclusion: The results justify using automated NAATs such as the Xpert MTB/RIF assay as the initial diagnostic modality to expedite management in HIV-infected patients.en_ZA
dc.description.urihttp://www.samj.org.za/index.php/samj/article/view/7492
dc.format.extent2 pagesen_ZA
dc.language.isoen_ZAen_ZA
dc.publisherHealth & Medical Publishing Groupen_ZA
dc.subjectNeedle biopsyen_ZA
dc.subjectTuberculosis -- Diagnostic imagingen_ZA
dc.subjectHIV (Viruses)en_ZA
dc.subjectLymphadenopathyen_ZA
dc.subjectHIV-positive personsen_ZA
dc.titleDiagnostic yield of fine needle aspiration biopsy in HIV-infected adults with suspected mycobacterial lymphadenitisen_ZA
dc.typeArticleen_ZA
dc.description.versionPublisher's versionen_ZA
dc.rights.holderSouth African Medical Journalen_ZA


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