Now showing items 1-3 of 3
A comparison of biomarker based incidence estimators
(Public Library of Science (PLOS), 2009-10)
Background: Cross-sectional surveys utilizing biomarkers that test for recent infection provide a convenient and cost effective way to estimate HIV incidence. In particular, the BED assay has been developed for this purpose. ...
Population-level HIV incidence estimates using a combination of synthetic cohort and recency biomarker approaches in KwaZulu-Natal, South Africa
(Public Library of Science, 2018-09-13)
Introduction: There is a notable absence of consensus on how to generate estimates of population-level incidence. Incidence is a considerably more sensitive indicator of epidemiological trends than prevalence, but is harder ...
Computational analysis of antibody dynamics identifies recent HIV-1 infection
(American Society for Clinical Investigation, 2018)
Accurate HIV-1 incidence estimation is critical to the success of HIV-1 prevention strategies. Current assays are limited by high false recent rates (FRRs) in certain populations and a short mean duration of recent infection ...