Now showing items 1-3 of 3
Recalibration of the limiting antigen avidity EIA to determine mean duration of recent infection in divergent HIV-1 subtypes
(Public Library of Science, 2015)
Background: Mean duration of recent infection (MDRI) and misclassification of long-term HIV-1 infections, as proportion false recent (PFR), are critical parameters for laboratory-based assays for estimating HIV-1 ...
Seroconverting blood donors as a resource for characterising and optimising recent infection testing algorithms for incidence estimation
(Public Library of Science, 2011-06-09)
Introduction: Biomarker-based cross-sectional incidence estimation requires a Recent Infection Testing Algorithm (RITA) with an adequately large mean recency duration, to achieve reasonable survey counts, and a low ...
Interpreting HIV diagnostic histories into infection time estimates : analytical framework and online tool
(BMC (part of Springer Nature), 2019-10-26)
Background: It is frequently of epidemiological and/or clinical interest to estimate the date of HIV infection or time-since-infection of individuals. Yet, for over 15 years, the only widely-referenced infection dating ...