Now showing items 1-3 of 3
Population-level HIV incidence estimates using a combination of synthetic cohort and recency biomarker approaches in KwaZulu-Natal, South Africa
(Public Library of Science, 2018-09-13)
Introduction: There is a notable absence of consensus on how to generate estimates of population-level incidence. Incidence is a considerably more sensitive indicator of epidemiological trends than prevalence, but is harder ...
Interpreting HIV diagnostic histories into infection time estimates : analytical framework and online tool
(BMC (part of Springer Nature), 2019-10-26)
Background: It is frequently of epidemiological and/or clinical interest to estimate the date of HIV infection or time-since-infection of individuals. Yet, for over 15 years, the only widely-referenced infection dating ...
Computational analysis of antibody dynamics identifies recent HIV-1 infection
(American Society for Clinical Investigation, 2018)
Accurate HIV-1 incidence estimation is critical to the success of HIV-1 prevention strategies. Current assays are limited by high false recent rates (FRRs) in certain populations and a short mean duration of recent infection ...