Now showing items 1-6 of 6
Antiretroviral therapy for prevention of tuberculosis in adults with HIV : a systematic review and Meta-Analysis
(Public Library of Science, 2012-07)
Background: Human immunodeficiency virus (HIV) infection is the strongest risk factor for developing tuberculosis and has fuelled its resurgence, especially in sub-Saharan Africa. In 2010, there were an estimated 1.1 ...
HIV treatment as prevention : debate and commentary : will early infection compromise treatment-as-prevention strategies?
(Public Library of Science (PLOS), 2012-07)
Universal HIV testing and immediate antiretroviral therapy for infected individuals has been proposed as a way of reducing the transmission of HIV and thereby bringing the HIV epidemic under control. It is unclear whether ...
The potential impact of male circumcision on HIV in Sub-Saharan Africa
(Public Library of Science -- PLoS, 2006-07)
Background A randomized controlled trial (RCT) has shown that male circumcision (MC) reduces sexual transmission of HIV from women to men by 60% (32% 76%; 95% CI) offering an intervention of proven efficacy for reducing ...
Clinical prognostic value of RNA viral load and CD4 cell counts during untreated HIV-1 infection : a quantitative review
(Public Library of Science, 2009-16-07)
Background: The prognostic value of CD4 counts and RNA viral load for identifying treatment need in HIV-infected individuals depends on (a) variation within and among individuals, and (b) relative risks of clinical progression ...
Nutrition, diabetes and tuberculosis in the epidemiological transition
(Public Library of Science (PLOS), 2011-06)
Background: Diabetes prevalence and body mass index reflect the nutritional profile of populations but have opposing effects on tuberculosis risk. Interactions between diabetes and BMI could help or hinder TB control in ...
Dynamics and control of infections on social networks of population types
Random mixing in host populations has been a convenient simplifying assumption in the study of epidemics, but neglects important differences in contact rates within and between population groups. For HIV/AIDS, the ...