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Isoniazid preventive therapy in HIV-infected and -uninfected children (0 - 14 years)

dc.contributor.authorSchaaf, Hendrik S.en_ZA
dc.contributor.authorCotton, Mark F.en_ZA
dc.contributor.authorBoon, Gerald P. G.en_ZA
dc.contributor.authorJeena, Prakash M.en_ZA
dc.date.accessioned2014-07-07T12:33:10Z
dc.date.available2014-07-07T12:33:10Z
dc.date.issued2013-09-04
dc.identifier.citationSchaaf, H. S., Cotton, M. F., Boon, G. P. G. & Jeena, P. M. 2013. Isoniazid preventive therapy in HIV-infected and -uninfected children (0 - 14 years). South African Medical Journal, 103(10):714-715, doi:10.7196/SAMJ.7189.en_ZA
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.otherdoi:10.7196/SAMJ.7189
dc.identifier.urihttp://hdl.handle.net/10019.1/94760
dc.descriptionCITATION: Schaaf, H. S., Cotton, M. F., Boon, G. P. G. & Jeena, P. M. 2013. Isoniazid preventive therapy in HIV-infected and -uninfected children (0 - 14 years). South African Medical Journal, 103(10):714-715, doi:10.7196/SAMJ.7189.en_ZA
dc.descriptionThe original publication is available at http://www.samj.org.zaen_ZA
dc.description.abstractIsoniazid preventive therapy (IPT) prevents tuberculosis (TB) in immunocompetent children <5 years of age after exposure to an infectious TB source case. Routine IPT has been advocated in all HIV-infected children without TB, but has been controversial. Antiretroviral therapy markedly reduces the risk for TB in HIV-infected children, especially when started early in infancy. In HIV-infected children, as in HIV- uninfected children, we recommend post-exposure IPT after each TB exposure episode; but in HIV-infected children, this should be given irrespective of age or antiretroviral therapy. However, evidence for routine IPT without known exposure to TB in HIV-infected children is not convincing and is therefore not recommended.en_ZA
dc.description.urihttp://www.samj.org.za/index.php/samj/article/view/7189
dc.format.extent2 pagesen_ZA
dc.language.isoen_ZAen_ZA
dc.publisherHealth & Medical Publishing Groupen_ZA
dc.subjectIsoniazid preventive therapyen_ZA
dc.subjectHIV-positive childrenen_ZA
dc.subjectTuberculosis in children -- Preventionen_ZA
dc.titleIsoniazid preventive therapy in HIV-infected and -uninfected children (0 - 14 years)en_ZA
dc.typeArticleen_ZA
dc.description.versionPublisher's versionen_ZA
dc.rights.holderAuthors retain copyrighten_ZA


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