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Emergence of levofloxacin-non-susceptible Streptococcus pneumoniae and treatment for multidrug-resistant tuberculosis in children in South Africa: a cohort observational surveillance study

von Gottberg A.; Klugman K.P.; Cohen C.; Wolter N.; de Gouveia L.; du Plessis M.; Mpembe R.; Quan V.; Whitelaw A.; Hoffmann R.; Govender N.; Meiring S.; Smith A.M.; Schrag S. (2008)

Background: Use of fluoroquinolones to treat paediatric cases of multidrug-resistant tuberculosis could affect the emergence of resistance to this class of drugs. Our aim was to estimate the incidence of, and risk factors ...