Neonatal pancreatic function in infants born to mothers with gestational and overt diabetes

Date
1984-11
Authors
De Villiers, T. J.
MacFarlane, C. M.
Tsakalakos, N.
Taljaard, J. J. F.
Journal Title
Journal ISSN
Volume Title
Publisher
Health and Medical Publishing Group -- HMPG
Abstract
Neonatal pancreatic function was assessed in infants born to non-diabetic mothers and to mothers with well-controlled gestational diabetes (GD) and overt diabetes (OD) using cord blood C-peptide estimations and the calculation of cord C-peptide/glucose ratios. Exaggerated pancreatic function was present in infants born to mothers with GD. In these infants the increased cord C-peptide values and cord C-peptide/glucose ratios correlated with their increased birth weight ratios. These results could not be explained on the basis of maternal hyperglycaemia and a possible intrinsic difference in pancreatic response between infants born to mothers with GD and those born to mothers with OD is suggested.
Description
The original publication is available at http://www.samj.org.za
Keywords
Diabetes in pregnancy, Newborn infants -- Family relationships
Citation
De Villiers, T. J. et al. 1984. Neonatal pancreatic function in infants born to mothers with gestational and overt diabetes. South African Medical Journal, 3 November: 690-693.