Aspects of dyslipidaemia in diabetes mellitus

Maritz, F. J. (1997)

CITATION: Maritz, F. J. 1997. Aspects of dyslipidaemia in diabetes mellitus. South African Medical Journal, 87(3):373-376.

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Dyslipidaemia in diabetes was referred to by Joslin as early as 19271 and has been the subject of numerous articles.2.... Very often little attention is paid to dyslipidaemia, which plays a major role in the premature development of atherosclerosis in diabetes. It is now increasingly recognised that diabetes is not only a disorder of carbohydrate metabolism but also of lipid and protein metabolism, and attention should be given to these other metabolic aspects and not only the glycaemic control of the diabetic patient. This article is not intended to be exhaustive, but aims rather to focus attention on the importance of dyslipidaemia in the management of diabetic patients. An overview is given of some of the pathophysiological processes that lead to dyslipidaemia in diabetes, the changes in lipids and lipoproteins that are seen are briefly described, and an outline of the management is presented.

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