'n Nuwe metode vir die bepaliog van serotonien in bloed en serebrospinale vloeistof

Kriek, J. A. ; Bester, A. J. ; Rossouw, J. J. (1979)

The original publication is available at http://www.samj.org.za

CITATION: Kriek, J. A., Bester, A. J. & Rossouw, J. J. 1979. 'n Nuwe metode vir die bepaliog van serotonien in bloed en serebrospinale vloeistof. South African Medical Journal, 55:260-262.

Article

A new rapid method for the microdetermination of serotonin (5-hydroxytryptamine) in plasma and cerebrospinal fluid is described. A recovery coefficient of 98% was obtained in the present method, with the use of [3H]-hydroxytryptamine creatinine sulphate as an internal standard, compared with recovery coefficients of 31% and 66% for the two existing methods generally used for serotonin determination. This method involves a one-step sample deproteinization by perchloric acid, resulting in a high stability of serotonin.

Please refer to this item in SUNScholar by using the following persistent URL: http://hdl.handle.net/10019.1/7667
This item appears in the following collections: