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Oral v. pulse intravenous cyclophosphamide : a retrospective analysis of adverse events in a setting with a high burden of infectious disease
(Health & Medical Publishing Group, 2015)
Background. Cyclophosphamide (CPM) is still considered to be the first-line treatment for many life-threatening autoimmune conditions. It does, however, carry a significant risk of serious adverse events, especially ...
Enhanced oxidative stress and other potential biomarkers for retinopathy in type 2 diabetics : beneficial effects of the nutraceutic supplements
(Hindawi, 2015)
We have studied the global risk of retinopathy in a Mediterranean population of type 2 diabetes mellitus (T2DM) patients, according to clinical, biochemical, and lifestyle biomarkers. The effects of the oral supplementation ...
Multiscale complexity analysis of the cardiac control identifies asymptomatic and symptomatic patients in long QT syndrome type 1
(PLoS, 2014-04-04)
The study assesses complexity of the cardiac control directed to the sinus node and to ventricles in long QT syndrome type 1 (LQT1) patients with KCNQ1-A341V mutation. Complexity was assessed via refined multiscale entropy ...
Oral versus pulse intravenous cyclophosphamide: a retrospective analysis of adverse events in a high infectious diseases burdened setting
(Stellenbosch : Stellenbosch University, 2014-01-14)
ENGLISH ABSTRACT: Background
Cyclophosphamide (CPM) is still considered to be the first line treatment of many life-threatening
autoimmune conditions. It does however carry significant risk for severe adverse events ...
Challenges in biobank governance in Sub-Saharan Africa
(BioMed Central, 2013-09)
Background: Biological sample and data transfer within and out of Africa is steeped in controversy With the
H3Africa project now aiming to establish biobanks in Africa, it is essential that there are ethical and ...
Discourse of final-year medical students during clinical case presentations
(Health and Medical Publishing Group (HMPG), 2011-06)
Introduction: The need for medical students to adopt a discourse appropriate
to the field is repeatedly emphasised by teaching staff during
lectures and ward rounds. The acquisition of such discourse is
often not assessed, ...
Patients as consumers of health care in South Africa : the ethical and legal implications
(BioMed Central, 2013-03)
Background
South Africa currently has a pluralistic health care system with separate public and private
sectors. It is, however, moving towards a socialised model with the introduction of National
Health Insurance. The ...
Advancing research ethics training in Southern Africa (ARESA)
(Health and Medical Publishing Group (HMPG), 2012-12)
Southern Africa is a research-rich environment in which research ethics review is critical. The research ethics review system is well established but considerable variability in capacity and training exists among the various ...
Perceived barriers for accessing health services among individuals with disability in four African countries
(Public Library of Science, 2015)
ENGLISH ABSTRACT: There is an increasing awareness among researchers and others that marginalized and vulnerable groups face problems in accessing health care. Access problems in particular in low-income countries may ...
An optimized background regimen design to evaluate the contribution of levofloxacin to multidrug-resistant tuberculosis treatment regimens : study protocol for a randomized controlled trial
(BioMed Central, 2017-11-25)
Background:
Current guidelines for treatment of multidrug-resistant tuberculosis (MDR-TB) are largely based on expert opinion and observational data. Fluoroquinolones remain an essential part of MDR-TB treatment, but ...