• The real value of endobronchial ultrasound 

      Vorster, Morne Johan; Schubert, Pawel Tomasz; Koegelenberg, Coenraad Frederik Nicolaas (Health and Medical Publishing Group, 2015)
      Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has become a standard procedure worldwide, used in conjunction with bronchoscopy to obtain biopsies for mediastinal disorders. A 67-year-old man ...
    • Recommendations for the use of bronchial thermoplasty in the management of severe asthma 

      Dheda, Keertan; Koegelenberg, Coenraad F. N.; Esmail, Aliasgar; Irusen, Elvis; Wechsler, Michael; Niven, Rob M.; Bateman, Eric D.; Chung, Kian Fan (Health & Medical Publishing Group, 2015)
      There are approximately 3 million asthma suffers in South Africa, and the national death rate is ranked as one of the highest in the world. Approximately 5% have severe asthma (uncontrolled despite being adherent on maximal ...
    • Toxicity related to standard TB therapy for pulmonary tuberculosis and treatment outcomes in the REMoxTB study according to HIV status 

      Tweed, Conor D.; Crook, Angela M.; Dawson, Rodney; Diacon, Andreas H.; McHugh, Timothy D.; Mendel, Carl M.; Meredith, Sarah K.; Mohapi, Lerato; Murphy, Michael E.; Nunn, Andrew J.; Phillips, Patrick P. J.; Singh, Kasha P.; Spigelman, Melvin; Gillespie, Stephen H. (BMC (part of Springer Nature), 2019-08-14)
      Background: The phase III REMoxTB study prospectively enrolled HIV-positive (with CD4+ count > 250 cells, not on anti-retroviral therapy) and HIV-negative patients. We investigated the incidence of adverse events and cure ...
    • Tricyclic antidepressant overdose necessitating ICU admission 

      Koegelenberg, Coenraad F. N.; Joubert, Zirkia J.; Irusen, Elvis M. (Health and Medical Publishing Group (HMPG), 2012-05)
      Tricyclic antidepressant (TCA) overdose necessitating intensive care unit (ICU) admission remains a significant problem in the Western Cape. In this retrospective study, we reviewed the course of life-threatening TCA ...
    • The utility of Xpert MTB/RIF performed on bronchial washings obtained in patients with suspected pulmonary tuberculosis in a high prevalence setting 

      Barnard, Dewald A.; Irusen, Elvis M.; Bruwer, Johannes W.; Plekker, Dante; Whitelaw, Andrew C.; Deetlefs, Jacobus D.; Koegelenberg, Coenraad F. N. (BioMed Central, 2015-09-16)
      Background: Xpert MTB/RIF has been shown to have a superior sensitivity to microscopy for acid fast bacilli (AFB) in sputum and has been recommended as a standard first line investigation for pulmonary tuberculosis ...
    • Validation of a severity-of-illness score in patients with tuberculosis requiring intensive care unit admission 

      Koegelenberg, Coenraad Frederik N.; Balkema, Cecile A.; Jooste, Ynishia; Taljaard, Jantjie J.; Irusen, Elvis M. (Health & Medical Publication Group, 2015-05-27)
      Background. There is a paucity of data on the determinants of mortality due to tuberculosis (TB) in the intensive care unit (ICU). Objective. To develop a simple severity-of-illness score for use in patients with TB admitted ...