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Clinical findings and genetic screening for copy number variation mutations in a cohort of South African patients with Parkinson’s disease
(Health & Medical Publishing Group, 2016)
ENGLISH ABSTRACT: Background. Parkinson’s disease (PD), with a prevalence of up to 4% in Western countries, appears to be less common in Africa, possibly in part because of genetic factors. African studies investigating ...
Listerial brainstem encephalitis – treatable, but easily missed
(Health & Medical Publishing Group, 2015)
ENGLISH ABSTRACT: Listerial brainstem encephalitis (LBE) is an uncommon form of listerial central nervous system infection that progresses rapidly and is invariably fatal unless detected and treated early. We report on six ...
Reliability and diagnostic performance of CT imaging criteria in the diagnosis of Tuberculous Meningitis
(PLOS One, 2012-06)
Introduction: Abnormalities on CT imaging may contribute to the diagnosis of tuberculous meningitis (TBM). Recently, an
expert consensus case definition (CCD) and set of imaging criteria for diagnosing basal meningeal ...
Stem cell therapy and amyotrophic lateral sclerosis
(Health and Medical Publishing Group (HMPG), 2012-06)
We have been made aware of several patients with
neurological diseases attending stem cell therapy centres, and in
particular individuals with amyotrophic lateral sclerosis (ALS). The
opening of stem cell clinics in ...
A putative founder effect for Parkinson’s disease in South African Afrikaners
(Health & Medical Publishing Group, 2014-06)
There is evidence for a founder effect for Parkinson’s disease in South African Afrikaners. This finding is of importance for two reasons. Firstly, given that established genetic causes of PD have not been identified in ...
EEG source connectivity to localize the seizure onset zone in patients with drug resistant epilepsy
(Elsevier, 2017-09)
ENGLISH ABSTRACT: the presurgical evaluation of epilepsy as a reflection of the irritative zone. ESI of ictal scalp EEG to localize the
seizure onset zone (SOZ) remains challenging. We investigated the value of an approach ...
Peritoneal dialysis technique survival at Tygerberg Hospital in Cape Town, South Africa
(African Association of Nephrology, 2017)
Background: The use of peritoneal dialysis (PD) as a treatment modality for patients with end-stage renal disease (ESRD) has been declining in many countries over the past few years. One of the reasons is technique failure, ...