• Calcific uraemic arteriolopathy (calciphylaxis) in patients on renal replacement therapy 

      Sebastian, S.; Jordaan, H. F.; Schneider, J. W.; Moosa, M. R.; Davids, M. R. (Health and Medical Publishing Group, 2017)
      Background. Calcific uraemic arteriolopathy (calciphylaxis) is an unusual and potentially fatal condition characterised by small-vessel calcification and ischaemic skin necrosis. It mainly affects patients with end-stage ...
    • Development and evaluation of a multimedia e-learning resource for electrolyte and acid-base disorders 

      Davids, MR; Chikte, Usuf M. E.; Halperin, Mitchell L. (American Physiological Society, 2011-10)
      This article reports on the development and evaluation of a Web-based application that provides instruction and hands-on practice in managing electrolyte and acid-base disorders. Our teaching approach, which focuses on ...
    • Effect of improving the usability of an e-learning resource : a randomized trial 

      Davids, Mogamat Razeen; Chikte, Usuf M. E.; Halperin, Mitchell L. (HighWire, 2014-06)
      Optimizing the usability of e-learning materials is necessary to reduce extraneous cognitive load and maximize their potential educational impact. However, this is often neglected, especially when time and other resources ...
    • An effective approach to chronic kidney disease in South Africa 

      Moosa, Mohammed Rafique; Meyers, Anthony M.; Gottlich, Errol; Naicker, Sarala (Health & Medical Publishing Group, 2016)
      ENGLISH ABSTRACT: Very few patients with end-stage kidney disease in South Africa receive renal replacement treatment (RRT), despite the rapidly growing demand, because of resource constraints. Nephrologists who agonise ...
    • Gitelman syndrome in a South African family presenting with hypokalaemia and unusual food cravings 

      Van der Merwe, Pieter Du Toit; Rensburg, Megan A.; Haylett, William L.; Bardien, Soraya; Davids, M. Razeen (BioMed Central, 2017-01-26)
      Background Gitelman syndrome (GS) is an autosomal recessive renal tubular disorder characterised by renal salt wasting with hypokalaemia, metabolic alkalosis, hypomagnesaemia and hypocalciuria. It is caused by mutations ...
    • Hypernatraemia in South African hospitalized patients 

      Abohajir, Ali; Rensburg, Megan A.; Davids, M. Razeen (African Association of Nephrology, 2019)
      Background: Hypernatraemia is a common electrolyte problem in hospitalized patients and is associated with a high mortality rate. We determined the incidence, causes, management, and outcomes of hypernatraemia in ...
    • Hypodipsic-hypernatremia syndrome in an adult with polycythemia : a case report 

      Chothia, Mogamat-Yazied; George, Kiran; Sheik, Muhammed; Davids, Mogamat Razeen (BMC (part of Springer Nature), 2018-12-27)
      Background: Hypernatremia is a very common electrolyte disorder and is frequently encountered in out-patient as well as in-hospital settings. We describe an adult who was found to have unexplained relative polycythemia ...
    • Impact of age, gender and race on patient and graft survival following renal transplantation - developing country experience 

      Moosa, M. Rafique (Health & Medical Publishing Group, 2003)
      Background. Optimising renal allograft survival is crucially important in developing countries because of limited resources to treat irreversible renal failure. However, although many factors can be manipulated to improve ...
    • Important causes of chronic kidney disease in South Africa 

      Moosa, M. R.; Van der Walt, I.; Naicker, S.; Meyers, A. M. (Health & Medical Publishing Group, 2015)
      In hypertensive patients without chronic kidney disease (CKD) the goal is to keep blood pressure (BP) at ≤140/90 mmHg. When CKD is present, especially where there is proteinuria of ≥0.5 g/day, the goal is a BP of ≤130/80 ...
    • Intradialytic hypertension during chronic haemodialysis and subclinical fluid overload assessed by bioimpedance spectroscopy 

      Sebastian, Sajith; Filmalter, Christelle; Harvey, Justin; Chothia, Mogamat-Yazied (Oxford University Press European Renal Association, 2016-06-19)
      Background: Intradialytic hypertension (IDH) increases morbidity and mortality. The prevalence in South Africa is unknown. The pathogenesis is unclear, but it has been suggested that IDH may be due to subclinical fluid ...
    • Misuse of blood 

      Burman, N. D. (HMPG, 1977-11)
      LETTER: In recent months an increasing number of patients have been referred to us by doctors from outside with a standard note: "... breathlessness ... tiredness ... anaemia (4-8 g/100 ml) ... blood transfusion given ... ...
    • Pattern of renal amyloidosis in South Africa 

      Hassen, Muhammed; Bates, William; Moosa, Mohammed R. (BMC (part of Springer Nature), 2019-11-09)
      Background: Kidney disease is a serious manifestation of systemic amyloidosis and a major cause of morbidity and mortality. Tuberculosis (TB) occurs up to 27 times more commonly in human immunodeficiency virus (HIV) ...
    • Prevalence of chronic kidney disease and association with cardiovascular risk factors among teachers in Cape Town, South Africa 

      Adeniyi, Aderemi B.; Laurence, Carien E.; Volmink, Jimmy A.; Davids, M. Razeen (Oxford University Press, 2017)
      Background: There is a need to determine the feasibility of conducting studies of chronic diseases among large cohorts of African patients. One aim of the South African feasibility study was to determine the prevalence ...
    • Quality of life in patients on chronic dialysis in South Africa : a comparative mixed methods study 

      Tannor, Elliot K.; Archer, Elize; Kapembwa, Kenneth; Van Schalkwyk, Susan C.; Davids, M. Razeen (BioMed Central, 2017-01-05)
      Background: The increasing prevalence of treated end-stage renal disease and low transplant rates in Africa leads to longer durations on dialysis. Dialysis should not only be aimed at prolonging lives but also improve ...
    • Recombinant human erythropoietin in end-stage renal disease 

      Bihl, G. (Health & Medical Publishing Group, 2002)
      [No abstract available]
    • A renal registry for Africa : first steps 

      Davids, M. Razeen; Eastwood, John B.; Selwood, Neville H.; Arogundade, Fatiu A.; Ashuntantang, Gloria; Gharbi, Mohammed Benghanem; Jarraya, Faical; MacPhee, Iain A. M.; McCulloch, Mignon; Plange-Rhule, Jacob; Swanepoel, Charles R.; Adu, Dwomoa (Oxford University Press European Renal Association, 2016)
      ENGLISH ABSTRACT: There is a dearth of data on end-stage renal disease (ESRD) in Africa. Several national renal registries have been established but have not been sustainable because of resource limitations. The African ...
    • Residual renal function in chronic dialysis is not associated with reduced erythropoietin-stimulating agent dose requirements : a cross-sectional study 

      Louw, Elizabeth Helene; Chothia, Mogamat-Yazied (BioMed Central, 2017-11-25)
      Background: Anaemia is a very common problem in patients with end-stage kidney disease (ESKD) and the use of erythropoietin-stimulating agents (ESA) has revolutionised its treatment. Residual renal function (RRF) is ...
    • The role of the endothelium in the reduction of restenosis following balloon angioplasty 

      Davids, MR; Page, C.; Muller, C. J.; Rossouw, D. J.; Doubell, A. F. (Clinics Cardive Publishing, 1998-10)
      Objective. Coronary angioplasty is complicated in one-third of cases by restenosis due to intimal hyperplasia. This is the result of the migration and proliferation of vascular smooth-muscle cells (SMCs) and correlates ...
    • Salivary creatinine as a diagnostic tool for evaluating patients with chronic kidney disease 

      Temilola, Dada O.; Bezuidenhout, Karla; Erasmus, Rajiv T.; Stephen, Lawrence; Davids, Mogamat R.; Holmes, Haly (BMC (part of Springer Nature), 2019-10-29)
      Background: Preliminary studies have shown the potential use of salivary creatinine concentration in the diagnosis of chronic kidney disease (CKD). For saliva to replace serum as a diagnostic tool, studies must be done ...
    • Strengthening renal registries and ESRD research in Africa 

      Davids, M. Razeen; Caskey, Fergus J.; Young, Taryn; Balbir Singh, Gillian K. (Elsevier, 2017)
      ENGLISH ABSTRACT: In Africa the combination of non-communicable diseases, infectious diseases, exposure to environmental toxins and acute kidney injury related to trauma and childbirth are driving an epidemic of chronic ...