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Lipoatrophy/lipohypertrophy outcomes after antiretroviral therapy switch in children in the UK/Ireland (Public Library of Science, 2017)Background: Following widespread use of stavudine, a thymidine analogue, in antiretroviral therapy (ART) over the past three decades, up to a third of children developed lipoatrophy (LA) and/or lipohypertrophy (LH). ...
HIV viral load as an independent risk factor for tuberculosis in South Africa : collaborative analysis of cohort studies (Wiley Open Access, 2017)Introduction: Chronic immune activation due to ongoing HIV replication may lead to impaired immune responses against opportunistic infections such as tuberculosis (TB). We studied the role of HIV replication as a risk ...