• An 8-year retrospective study of adult and paediatric Burkitt’s lymphoma at Tygerberg Hospital, South Africa 

      Musekwa, Ernest; Chapanduka, Zivanai C.; Bassa, Fatima; Kruger, Mariana (AOSIS, 2020-04-30)
      Background: Burkitt lymphoma(BL) is a high grade non-Hodgkin lymphoma, which may be underdiagnosed in South Africa, due to a high burden of infectious diseases such as HIV and TB which may present with similar clinical ...
    • Adult T-cell leukaemia / lymphoma in an adolescent patient : expect the unexpected 

      Abdullah, Ibtisam; Nell, Erica-Mari; Chapanduka, Zivanai C. (AOSIS, 2020-05-25)
      ENGLISH ABSTRACT: This case study explores a clinicopathological presentation of Adult T-cell leukaemia/lymphoma (ATLL) at Tygerberg Hospital; a disease associated with adulthood noted in an adolescent patient. Adult T-cell ...
    • Age and race distribution of patients who undergo haematological investigations at Tygerberg Hospital (Afrikaans) 

      Brink S.; Van Schalkwyk D.J.; Steytler J.G. (HMPG, 1977-11)
      The race, age and sex of patients referred for peripheral blood investigations at the Tygerberg Hospital were analysed statistically. An IBM 370/158 computer was used. Two groups were compared. The first was a 'low Hb ...
    • Aplasia versus pancytopenia, including the pure red cell variant 

      Jacobs, Peter; Wood, Lucille (Health and Medical Publishing Group (HMPG), 2012-09)
      This is the first in our third series of clinical vignettes that are centred on everyday presentations. Each emphasises practical aspects of team-based care, having relevance for general practitioners, specialists and ...
    • Association of deworming with reduced eosinophilia : implications for HIV/AIDS and co-endemic diseases 

      Fincham, J. E.; Markus, M. B.; Adams, V. J.; Lombard, C. J.; Bentwich, Z.; Mansvelt, E. P. G.; Dhansay, M. A.; Schoeman, S. E. (Academy of Science of South Africa, 2003-04)
      Eosinophil counts in venous blood were monitored during a randomized controlled deworming trial (n = 155 children) that lasted for a year, and in a whole-school deworming programme (range 174-256 children) of 2 years' ...
    • B-cell and T-cell activation in South African HIV-1-positive non-Hodgkin’s lymphoma patients 

      Flepisi, Brian T.; Bouic, Patrick; Sissolak, Gerhard; Rosenkranz, Bernd (Medpharm Publications, 2018)
      Background: Altered immune mechanisms play a critical role in the pathogenesis of non-Hodgkin’s lymphoma (NHL). HIV-1 (HIV) infection is associated with a state of excessive T-cell activation, which can lead to increased ...
    • Between a rock and a hard place : COVID-19 and South Africa’s response 

      Staunton, Ciara; Swanepoel, Carmen; Labuschagine, Melodie (Oxford University Press, 2020)
      The spread of COVID-19 across China, Asia, Europe and the United States of America was met with public health responses that initially encouraged hand washing and social distancing. They quickly turned to restrictions on ...
    • Biomarkers of HIV-associated cancer 

      Flepisi, Brian Thabile; Bouic, Patrick; Sissolak, Gerhard; Rosenkranz, Bernd (Libertas Academica, 2014)
      Cancer biomarkers have provided great opportunities for improving the management of cancer patients by enhancing the efficiency of early detection, diagnosis, and efficacy of treatment. Every cell type has a unique molecular ...
    • Bone marrow involvement in malignant lymphoma without peripheral lymphadenopathy 

      Staples, W. G.; Getaz, E. P. (HMPG, 1977-07)
      Twelve cases of non-Hodgkin's lymphoma and a single case of Hodgkin's disease were first diagnosed on bone marrow biopsy. None of the patients had superficially enlarged lymph nodes, and in 3 patients the histological ...
    • Castleman’s disease in the HIV-endemic setting 

      Mahroug, Esam-Rajab; Sher-Locketz, Candice; Desmirean, Minodora-Silvia; Abayomi, Emmanuel-Akinola; Tomuleasa, Ciprian; Grewal, Ravnit (Dove Medical Press, 2018)
      Introduction: Castleman’s disease (CD), first described by Benjamin Castleman in 1954, is a giant or angiofollicular lymph node hyperplasia, described as a rare monotypic polyclonal B-cell lymphoproliferative disorder with ...
    • Chronic myelomonocytic leukaemia: a case report 

      Getaz E.P.; Staples W.G. (HMPG, 1977)
      [No abstract available]
    • Clinical and haematological problems associated with severe abruptio placentae 

      Odendaal H.J.; Brink S.; Steytler J.G. (Health & Medical Publishing Group, 1978)
      A clinical study was done of 80 patients in whom abruptio placentae was severe enough to cause intra-uterine death of the fetus. Central venous pressure was measured whenever possible to ensure adequate fluid replacement. ...
    • Complete blood count reference intervals from a healthy adult urban population in Kenya 

      Omuse, Geoffrey; Maina, Daniel; Mwangi, Jane; Wambua, Caroline; Radia, Kiran; Kanyua, Alice; Kagotho, Elizabeth; Hoffman, Mariza; Ojwang, Peter; Premji, Zul; Ichihara, Kiyoshi; Erasmus, Rajiv (Public Library of Science, 2018)
      Background: There are racial, ethnic and geographical differences in complete blood count (CBC) reference intervals (RIs) and therefore it is necessary to establish RIs that are population specific. Several studies have ...
    • Cystic partially differentiated nephroblastoma-like lesion following neoadjuvant chemotherapy for nephroblastoma : a case report and review of the literature 

      Bruce-Brand, C.; Reyes-Mugica, M.; Van Zyl, A.; Schubert, P. T. (Elsevier, 2020)
      Cystic partially differentiated nephroblastoma (CPDN) and cystic nephroblastoma are paediatric renal tumours characterised by the presence of a variable combination of primitive epithelium, immature stroma and blastema. Cystic ...
    • Disseminated tuberculosis, bone marrow necrosis and lymphoma : a case report 

      Staples, W. G.; Getaz, E. P.; Botha, D. (Health & Medical Publishing Group, 1977)
      Tuberculosis often complicates lymphoma, and bone marrow necrosis has been described in disseminated tuberculosis. However, the association of lymphoma, disseminated tuberculosis and bone marrow necrosis is rare. We report ...
    • Effects of puff adder venom on coagulation, fibrinolysis and platelet aggregation in the baboon 

      Brink, S.; Steytler, J. G. (Health and Medical Publishing Group (HMPG), 1974)
      The in vitro and in vivo hematological effects of puff adder (Bitis arietans) venom in the baboon (Papio ursinus) with regard to its effect on coagulation, fibrinolysis and platelet aggregation were studied. There is a ...
    • 'n Epidemiologiese studie van perifere bloedondersoeke 

      Brink S.; Van Schalkwyk, D. J. (HMPG, 1979-08)
      A statistical random sample of 600 patients from the population referred to Tygerberg Hospital for peripheral blood investigations was analysed statistically with an IBM 370/158 computer. Suitable transformations ...
    • Familial Waldenstrom's macroglobulinaemia: a case report 

      Getaz, E. P.; Staples, W. G. (HMPG, 1977-06)
      A patient with Waldenstrom's macroglobulinemia, whose father died of the same condition, is presented. The literature on familial occurrence of paraproteinaemia is briefly reviewed.
    • Guideline for the treatment of myelodysplastic syndromes (MDS) in South Africa 

      Louw, V. J.; Bassa, F.; Chan, S. W.; Dreosti, L.; Du Toit, M.; Ferreira, M.; Gartrell, K.; Gunther, K.; Jogessar, V.; Littleton, N.; Mahlangu, J.; McDonald, A.; Patel, M.; Pool, R.; Ruff, P.; Schmidt, A.; Sissolak, G.; Swart, A.; Verburgh, E.; Webb, M. J. (Health and Medical Publishing Group (HMPG), 2011-12)
      Introduction. Myelodysplastic syndromes (MDS) encompass a heterogeneous group of clonal haematopoietic disorders characterised by chronic and progressive cytopenias resulting from ineffective haematopoiesis. Treatment ...
    • Guidelines for lupus anticoagulant testing in South Africa 

      Bailly, J.; Louw, S.; De Koker, A.; Potgieter, J. J. C.; Coetzee, M. J.; Chapanduka, Z. C.; Opie, J. J. (The Society of Medical Laboratory Technologists of South Africa, 2020)
      ENGLISH ABSTRACT: The lupus anticoagulant (LA) refers to the prolongation of certain coagulation tests due to the action of heterogenous autoantibodies. However, the LA is a misnomer since it is associated with thrombosis ...