Browsing Research Articles (Medical Microbiology) by Title
Now showing items 1-20 of 42
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Antibiotic stewardship ward rounds and a dedicated prescription chart reduce antibiotic consumption and pharmacy costs without affecting inpatient mortality or re-admission rates
(Public Library of Science, 2013-12-09)Background Antibiotic consumption is a major driver of bacterial resistance. To address the increasing burden of multi-drug resistant bacterial infections, antibiotic stewardship programmes are promoted worldwide to ... -
Antibiotic-resistant Serratia marcescens infection in a hospital
(HMPG, 1979-04)Over a 12-month period, 74 isolates of Serratia marcescens were obtained from various sources at Tygerberg Hospital. The majority of these isolates were from catheterized patients with urinary tract infections, and ... -
Antibody responses to vaccination among South African HIV-exposed and unexposed uninfected infants during the first 2 years of life
(American Society for Microbiology, 2013-01)HIV-exposed but uninfected (HEU) infants born to HIV-infected mothers from areas in the world with a high burden of infectious disease suffer higher infectious morbidity and mortality than their HIV unexposed uninfected ... -
An appraisal of the uricult dip slide method in the diagnosis of urinary infections
(HMPG, 1973-05)Uricult dip slide urine cultures were compared with standard laboratory plate cultures. Good agreement of bacterial counts was obtained after incubation at 37°C but not at room temperature. Tests of therapeutic activity ... -
The association between pathogen factors and clinical outcomes in patients with Staphylococcus aureus bacteraemia in a tertiary hospital, Cape Town
(Elsevier on behalf of International Society for Infectious Diseases, 2019-11-29)Background: Staphylococcus aureus is a serious pathogen, able to cause life-threatening infections such as bacteraemia. The association between S. aureus microbial characteristics and clinical outcomes is under- investigated ... -
B-cell and T-cell activation in South African HIV-1-positive non-Hodgkin’s lymphoma patients
(Medpharm Publications, 2018)Background: Altered immune mechanisms play a critical role in the pathogenesis of non-Hodgkin’s lymphoma (NHL). HIV-1 (HIV) infection is associated with a state of excessive T-cell activation, which can lead to increased ... -
Biofilm formation and adherence characteristics of an Elizabethkingia meningoseptica isolate from Oreochromis mossambicus
(BioMed Central, 2011-05-05)ABSTRACT: Background. Elizabethkingia spp. are opportunistic pathogens often found associated with intravascular device-related bacteraemias and ventilator-associated pneumonia. Their ability to exist as biofilm structures ... -
Biomarkers of HIV-associated cancer
(Libertas Academica, 2014)Cancer biomarkers have provided great opportunities for improving the management of cancer patients by enhancing the efficiency of early detection, diagnosis, and efficacy of treatment. Every cell type has a unique molecular ... -
Characteristics and outcome of children with juvenile dermatomyositis in Cape Town: a cross-sectional study
(BioMed Central, 2016-11-11)Background: Juvenile dermatomyositis (JDM) is a rare idiopathic inflammatory childhood myopathy of uncertain aetiology. The demographic and clinical presentation of JDM may differ by race and geographic regions. Few ... -
Deficiency of the seventh component of complement : a case report
(Health & Medical Publishing Group, 1991)Deficiency of the 7th component of the complement cascade was diagnosed in a white male with recurrent meningococcal infections. This deficiency has not previously been reported in South Africa. -
Differentiation of Klebsiella Enterobacter Serratia organisms
(Health and Medical Publishing Group (HMPG), 1975)Differentiation of 625 strains of bacteria which fulfilled the requirements laid down for the definition of Klebsielleae was carried out using 6 biochemical tests. 546 strains were identified as members of the genus ... -
The effect of storage conditions on microbial communities in stool
(Public Library of Science, 2020)Microbiome research has experienced a surge of interest in recent years due to the advances and reduced cost of next-generation sequencing technology. The production of high quality and comparable data is dependent on ... -
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Enzyme-linked immunosorbent assay for the detection of mycobacterial antigens in the cerebrospinal fluid in tuberculous meningitis
(Health & Medical Publishing Group, 1987)Fifty-three cerebrospinal fluid specimens from meningitis patients were investigated by enzyme-linked immunosorbent assay for detection of mycobacterial antigens. After heating at 56° C for 1 hour to eliminate nonspecific ... -
First report of Wohlfahrtiimonas chitiniclastica bacteraemia in South Africa
(Health & Medical Publishing Group, 2016)ENGLISH ABSTRACT: No abstract available -
In vitro activity of tigecycline and comparators against Gram-positive and Gram-negative isolates collected from the Middle East and Africa between 2004 and 2011
(Elsevier, 2014)The Tigecycline Evaluation and Surveillance Trial (T.E.S.T.) was established in 2004 to monitor longitudinal changes in bacterial susceptibility to numerous antimicrobial agents, specifically tigecycline. In this study, ... -
Involving African traditional health practitioners in HIV/AIDS interventions
(Health and Medical Publishing Group (HMPG), 2008)[No abstract available] -
Laboratory based antimicrobial resistance surveillance for Pseudomonas aeruginosa blood isolates from South Africa
(Journal of Infection in Developing Countries, 2018)Introduction: Antimicrobial resistant bacterial infections are widespread globally and increases in antimicrobial resistance presents a major threat to public health. Pseudomonas aeruginosa is an opportunistic healthcare ... -
Laboratory-acquired infections of Salmonella enterica serotype Typhi in South Africa : phenotypic and genotypic analysis of isolates
(BioMed Central, 2017-9)Background: Workers in clinical microbiology laboratories are exposed to a variety of pathogenic microorganisms. Salmonella species is among the most commonly reported bacterial causes of laboratory-acquired infections. ... -
Management of uncomplicated malaria
(Health and Medical Publishing Group (HMPG), 2008-06)The key issues in the successful management of malaria are early and accurate diagnosis and urgent treatment with effective drugs. Disease presentation is, however, not specific – progression to complicated disease may ...
