Browsing Research Articles (Medical Microbiology) by Title
Now showing items 1-20 of 28
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Antibiotic stewardship ward rounds and a dedicated prescription chart reduce antibiotic consumption and pharmacy costs without affecting inpatient mortality or re-admission rates
(Public Library of Science, 2013-12-09)Background Antibiotic consumption is a major driver of bacterial resistance. To address the increasing burden of multi-drug resistant bacterial infections, antibiotic stewardship programmes are promoted worldwide to ... -
Antibiotic-resistant Serratia marcescens infection in a hospital
(HMPG, 1979-04)Over a 12-month period, 74 isolates of Serratia marcescens were obtained from various sources at Tygerberg Hospital. The majority of these isolates were from catheterized patients with urinary tract infections, and ... -
Antibody responses to vaccination among South African HIV-exposed and unexposed uninfected infants during the first 2 years of life
(American Society for Microbiology, 2013-01)HIV-exposed but uninfected (HEU) infants born to HIV-infected mothers from areas in the world with a high burden of infectious disease suffer higher infectious morbidity and mortality than their HIV unexposed uninfected ... -
An appraisal of the uricult dip slide method in the diagnosis of urinary infections
(HMPG, 1973-05)Uricult dip slide urine cultures were compared with standard laboratory plate cultures. Good agreement of bacterial counts was obtained after incubation at 37°C but not at room temperature. Tests of therapeutic activity ... -
Biofilm formation and adherence characteristics of an Elizabethkingia meningoseptica isolate from Oreochromis mossambicus
(BioMed Central, 2011-05-05)ABSTRACT: Background. Elizabethkingia spp. are opportunistic pathogens often found associated with intravascular device-related bacteraemias and ventilator-associated pneumonia. Their ability to exist as biofilm structures ... -
Biomarkers of HIV-associated cancer
(Libertas Academica, 2014)Cancer biomarkers have provided great opportunities for improving the management of cancer patients by enhancing the efficiency of early detection, diagnosis, and efficacy of treatment. Every cell type has a unique molecular ... -
Characteristics and outcome of children with juvenile dermatomyositis in Cape Town: a cross-sectional study
(BioMed Central, 2016-11-11)Background: Juvenile dermatomyositis (JDM) is a rare idiopathic inflammatory childhood myopathy of uncertain aetiology. The demographic and clinical presentation of JDM may differ by race and geographic regions. Few ... -
Differentiation of Klebsiella Enterobacter Serratia organisms
(Health and Medical Publishing Group (HMPG), 1975)Differentiation of 625 strains of bacteria which fulfilled the requirements laid down for the definition of Klebsielleae was carried out using 6 biochemical tests. 546 strains were identified as members of the genus ... -
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First report of Wohlfahrtiimonas chitiniclastica bacteraemia in South Africa
(Health & Medical Publishing Group, 2016)ENGLISH ABSTRACT: No abstract available -
In vitro activity of tigecycline and comparators against Gram-positive and Gram-negative isolates collected from the Middle East and Africa between 2004 and 2011
(Elsevier, 2014)The Tigecycline Evaluation and Surveillance Trial (T.E.S.T.) was established in 2004 to monitor longitudinal changes in bacterial susceptibility to numerous antimicrobial agents, specifically tigecycline. In this study, ... -
Involving African traditional health practitioners in HIV/AIDS interventions
(Health and Medical Publishing Group (HMPG), 2008)[No abstract available] -
Laboratory-acquired infections of Salmonella enterica serotype Typhi in South Africa : phenotypic and genotypic analysis of isolates
(BioMed Central, 2017-9)Background: Workers in clinical microbiology laboratories are exposed to a variety of pathogenic microorganisms. Salmonella species is among the most commonly reported bacterial causes of laboratory-acquired infections. ... -
Management of uncomplicated malaria
(Health and Medical Publishing Group (HMPG), 2008-06)The key issues in the successful management of malaria are early and accurate diagnosis and urgent treatment with effective drugs. Disease presentation is, however, not specific – progression to complicated disease may ... -
Molecular characterization of Staphylococcus aureus isolates from various healthcare institutions in Nairobi, Kenya : a cross sectional study
(BioMed Central, 2016-09-20)Background: Staphylococcus aureus (S. aureus) has established itself over the years as a major cause of morbidity and mortality both within the community and in healthcare settings. Methicillin resistant S. aureus (MRSA) ... -
National sentinel site surveillance for antimicrobial resistance in Klebsiella pneumoniae isolates in South Africa, 2010-2012
(Health & Medical Publishing Group, 2014-08)Background. The increasing rates of antimicrobial resistance observed in the nosocomial pathogen Klebsiella pneumoniae are of major public health concern worldwide. Objectives. To describe the antibiotic susceptibility ... -
Obesity is associated with increased seminal insulin and leptin alongside reduced fertility parameters in a controlled male cohort
(BioMed Central, 2014)Background: Obesity appears to be associated with male reproductive dysfunction and infertility, although this has been inconsistent and inconclusive. Insulin and leptin are known mediators and modulators of the ... -
Ontogeny of toll-like receptor mediated cytokine responses of South African infants throughout the first year of life
(Public Library of Science, 2012-09-13)The first year of life represents a time of marked susceptibility to infections; this is particularly true for regions in sub-Saharan Africa. As innate immunity directs the adaptive immune response, the observed increased ... -
Plasmid-mediated mcr-1 colistin resistance in Escherichia coli and Klebsiella spp. clinical isolates from the Western Cape region of South Africa
(BioMed Central, 2017-08-03)Background: Colistin is a last resort antibiotic for the treatment of carbapenem-resistant Gram negative infections. Until recently, mechanisms of colistin resistance were limited to chromosomal mutations which confer a ... -
Pneumocystis pneumonia in South African children diagnosed by molecular methods
(BioMed Central, 2014-01)Abstract Background Pneumocystis pneumonia (PCP) is an important cause of hospitalization and mortality in HIV-infected children. However, the incidence of PCP has been underestimated ...
