Role of cultivation media in the development of yeast strains for large scale industrial use

Date
2005-11
Authors
Hahn-Hagerdal, Barbel
Karhumaa, Kaisa
Larsson, Christer U.
Gorwa-Grauslund, Marie
Gorgens, Johann
Van Zyl, Willem H.
Journal Title
Journal ISSN
Volume Title
Publisher
BioMed Central
Abstract
Abstract: The composition of cultivation media in relation to strain development for industrial application is reviewed. Heterologous protein production and pentose utilization by Saccharomyces cerevisiae are used to illustrate the influence of media composition at different stages of strain construction and strain development. The effects of complex, defined and industrial media are compared. Auxotrophic strains and strain stability are discussed. Media for heterologous protein production and for bulk bio-commodity production are summarized.
Description
Includes bibliography.
Keywords
Cultivation media, Yeast strains -- Cultivation, Yeasts
Citation
Hahn-Hägerdal, B, Karhumaa, K, Larsson, CU, Gorwa-Grauslund, M, Görgens, J & Van Zyl, WH 2005, 'Role of cultivation media in the development of yeast strains for large scale industrial use', Microbial Cell Factories, 4(1):31.