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Quetiapine augmentation of SRIs in treatment refractory obsessive-compulsive disorder : a double-blind, randomised, placebo-controlled study [ISRCTN83050762]

Carey, Paul D.; Vythillingum, Bavanisha; Seedat, Soraya; Muller, Jacqueline E.; Van Ameringen, Michael; Stein, Dan J. (BioMed Central, 2005-01)

Background: Although serotonin reuptake inhibitors are effective in the treatment of OCD, many patients fail to respond to these agents. Growing evidence from open-label and placebo-controlled trials suggests a role for ...

Obsessive compulsive disorder : prevalence in Xhosa-speaking schizophrenia patients

Niehaus, D. J. H.; Koen, L.; Muller, J.; Laurent, C.; Stein, D. J.; Lochner, C.; Seedat, S.; Mbanga, I.; Deleuze, J.-F.; Mallet, J.; Emsley, R. A. (Health & Medical Publishing Group, 2005)

Obsessive compulsive disorder (OCD) has been reported in up to 31% of schizophrenia sufferers. This study evaluated the presence of OCD in a Xhosa-speaking schizophrenia group. Xhosa patients (N = 509, including 100 sibships) ...

Prevalence of obsessive compulsive disorder in first- and multi-episode male patients with schizophrenia-spectrum disorders

Koen, L.; Oosthuizen, P. P.; Niehaus, D. J. H.; Emsley, R. A.; Muller, J. E.; Stein, D. J.; Keyter, N.; Lochner, C.; Seedat, S. (Health & Medical Publishing Group, 2003)

Studies suggest that obsessive compulsive disorder (OCD) is a prevalent disorder (7.8 - 31.7%) in patients with schizophrenia and first-episode psychosis.1,2 Despite the varied study designs that have been employed, ...

Obsessive-compulsive disorder and trichotillomania : a phenomenological comparison

Lochner, Christine; Seedat, Soraya; Du Toit, Pieter L.; Nel, Daniel G.; Niehaus, Dana J. H.; Sandler, Robin; Stein, Dan J. (BioMed Central, 2005-01)

Background: Similarities between obsessive-compulsive disorder (OCD) and trichotillomania (TTM) have been widely recognized. Nevertheless, there is evidence of important differences between these two disorders. Some authors ...