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Quetiapine augmentation of SRIs in treatment refractory obsessive-compulsive disorder : a double-blind, randomised, placebo-controlled study [ISRCTN83050762]

Carey, Paul D.; Vythillingum, Bavanisha; Seedat, Soraya; Muller, Jacqueline E.; Van Ameringen, Michael; Stein, Dan J. (BioMed Central, 2005-01)

Background: Although serotonin reuptake inhibitors are effective in the treatment of OCD, many patients fail to respond to these agents. Growing evidence from open-label and placebo-controlled trials suggests a role for ...

Co-occurrence of schizophrenia and obsessive compulsive disorder : a literature review

Emsley, R. A.; Stein, D. J.; Oosthuizen, P. (Health & Medical Publishing Group, 1999)

[No abstract available]

Obsessive compulsive disorder

Stein, D. J. (AOSIS, 2013)

This guideline focuses on the pharmacotherapy of obsessivecompulsive disorder (OCD). OCD is characterised by obsessions and compulsions. A number of other disorders are also characterised by repetitive thoughts and rituals ...

Pica and the obsessive-compulsive spectrum disorders

Stein, D. J.; Bouwer, C.; Van Heerden, B. (Health & Medical Publishing Group, 1996)

Background. The concept of a spectrum of obsessive-compulsive related disorders may have clinical and research heuristic value in the approach to disorders similar to obsessive-compulsive disorder (OCD) in respect of ...

Obsessive-compulsive disorder in black South Africans - A case series

Gangdev, P. S.; Stein, D. J.; Ruzibiza, J. B. (Health & Medical Publishing Group, 1996)

Background. Obsessive-compulsive disorder (OCD) has been shown to be highly prevalent in both developing and developed countries. Nevertheless, data on OCD in blacks, and black South Africans in particular, are limited. ...

D8/17 in obsessive-compulsive disorder and trichotillomania

Niehaus, D. J. H.; Knowles, J. A.; Van Kradenberg, J.; Du Toit, W. D.; Kaminer, D.; Seedat, S.; Daniels, W.; Cotton, M.; Brink, P.; Beyers, A. D.; Bouic, P.; Chapman, F.; Zabriskie, J. B.; Stein, D. J. (Health & Medical Publishing Group, 1999)

The finding that patients with Sydenham's chorea often demonstrate obsessive-compulsive disorder (OeD) has fostered increased interest in possible neuroimmunological mechanisms in OCD.' Increased expression of the ...

Obsessive compulsive disorder : prevalence in Xhosa-speaking schizophrenia patients

Niehaus, D. J. H.; Koen, L.; Muller, J.; Laurent, C.; Stein, D. J.; Lochner, C.; Seedat, S.; Mbanga, I.; Deleuze, J.-F.; Mallet, J.; Emsley, R. A. (Health & Medical Publishing Group, 2005)

Obsessive compulsive disorder (OCD) has been reported in up to 31% of schizophrenia sufferers. This study evaluated the presence of OCD in a Xhosa-speaking schizophrenia group. Xhosa patients (N = 509, including 100 sibships) ...

Prevalence of obsessive compulsive disorder in first- and multi-episode male patients with schizophrenia-spectrum disorders

Koen, L.; Oosthuizen, P. P.; Niehaus, D. J. H.; Emsley, R. A.; Muller, J. E.; Stein, D. J.; Keyter, N.; Lochner, C.; Seedat, S. (Health & Medical Publishing Group, 2003)

Studies suggest that obsessive compulsive disorder (OCD) is a prevalent disorder (7.8 - 31.7%) in patients with schizophrenia and first-episode psychosis.1,2 Despite the varied study designs that have been employed, ...

Obsessive-compulsive disorder and trichotillomania : a phenomenological comparison

Lochner, Christine; Seedat, Soraya; Du Toit, Pieter L.; Nel, Daniel G.; Niehaus, Dana J. H.; Sandler, Robin; Stein, Dan J. (BioMed Central, 2005-01)

Background: Similarities between obsessive-compulsive disorder (OCD) and trichotillomania (TTM) have been widely recognized. Nevertheless, there is evidence of important differences between these two disorders. Some authors ...

Symmetry symptoms in obsessive-compulsive disorder : clinical and genetic correlates

Lochner, Christine; McGregor, Nathaniel; Hemmings, Sian M. J.; Harvey, Brian H.; Breet, Elsie; Swanevelder, Sonja; Stein, Dan J. (Associacao Brasileira de Psiquiatria, 2016)

Objective: In obsessive-compulsive disorder (OCD), symmetry-related symptoms may be important. Although clinical correlates of symmetry-related symptoms have been identified in OCD, few data exist on genetic associations. ...