• Shorter telomere length : a potential susceptibility factor for HIV-associated neurocognitive impairments in South African woman 

      Malan-Muller, Stefanie; Hemmings, Sian M. J.; Spies, Georgina; Kidd, Martin; Fennema-Notestine, Christine; Seedat, Soraya (PLoS, 2013-03)
      The neuropathogenesis of the human immunodeficiency virus (HIV) may manifest as various neurocognitive impairments (NCI). HIV-positive individuals also have significantly shorter telomere length (TL) in peripheral blood ...
    • Sniffing out olfactory reference syndrome 

      Thomas, Eileen; Voges, Juane; Chiliza, Bonginkosi; Stein, Dan J.; Lochner, Christine (AOSIS Publishing, 2017)
      Olfactory reference syndrome is characterised by the erroneous belief that one emits an unpleasant body odour. This results in significant distress and is often accompanied by repetitive behaviour such as frequent showering ...
    • Social anxiety disorder 

      Seedat, S. (AOSIS Publishing, 2013-08-30)
      ENGLISH SUMMARY : According to epidemiological studies, rates of social anxiety disorder(SAD) or social phobia range from 3% to 16% in the generalpopulation. Social phobia and specific phobias have an earlier ageof onset ...
    • The socioeconomic profile of alcohol-attributable mortality in South Africa : a modelling study 

      Probst, Charlotte; Parry, Charles D. H.; Wittchen, Hans-Ulrich; Rehm, Jurgen (BioMed Central, 2018-06-25)
      Background: Globally, illness and life expectancy follow a social gradient that puts people of lower socioeconomic status (SES) at higher risk of dying prematurely. Alcohol consumption has been shown to be a factor ...
    • South Africa's salt reduction strategy : are we on track, and what lies ahead? 

      Webster, Jacqui; Crickmore, Christelle; Charlton, Karen; Steyn, Krisela; Wentzel-Viljoen, Edelweiss; Naidoo, Pamela (Health & Medical Publishing Group, 2017)
      On 2 September 2016, 25 local and international participants from various sectors met in Cape Town to take stock of South Africa (SA)’s progress in salt reduction and develop a roadmap for action. SA is centre stage on ...
    • The South African Society of Psychiatrists (SASOP) treatment guidelines for psychiatric disorders 

      Emsley, R.; Colin, F.; Flisher, A. J.; Grobler, G.; Hawkridge, S.; Potocnik, F. C.; Seedat, S.; Stein, D. J.; Swingler, D.; Szabo, C. P. (AOSIS Publishing, 2013-08)
      The South African Society of Psychiatrists (SASOP) Treatment Guidelines for Psychiatric Disorders have been developed in order to address the local need for guidelines in our unique clinical setting.
    • South African Stress and Health (SASH) study : 12-month and lifetime prevalence of common mental disorders 

      Herman, Allen A.; Stein, Dan J.; Seedat, Soraya; Heeringa, Steven G.; Moomal, Hashim; Williams, David R. (Health and Medical Publishing Group (HMPG), 2009)
      Background. The South African Stress and Health (SASH) study is the first large-scale population-based study of common mental disorders in the country. This paper provides data on the 12-month and lifetime prevalence of ...
    • SSRI use in pregnancy : evaluating the risks and benefits 

      Du Toit, El.; Thomas, E.; Koen, L.; Vythilingum, B.; Grobler, S.; Smith, N.; Niehaus, D. (AOSIS Publishing, 2015)
      Selective serotonin reuptake inhibitor (SSRI) antidepressants are considered the primary pharmacological treatment for moderate to severe depression during pregnancy. Data regarding the safety of their use during pregnancy ...
    • Staff and bed distribution in public sector mental health services in the Eastern Cape Province, South Africa 

      Sukeri, Kiran; Alonso-Betancourt, Orlando; Emsley, Robin A. (AOSIS Publishing, 2014-11)
      Background. The Eastern Cape Province of South Africa is a resource-limited province with a fragmented mental health service. Objective. To determine the current context of public sector mental health services in terms ...
    • Study protocol for a longitudinal study evaluating the impact of rape on women's health and their use of health services in South Africa 

      Abrahams, Naeemah; Seedat, Soraya; Lombard, Carl; Kengne, Andre P.; Myers, Bronwyn; Sewnath, Alesha; Mhlongo, Shibe; Ramjee, Gita; Peer, Nasheeta; Garcia-Moreno, Claudia; Jewkes, Rachel (BMJ Publishing Group, 2017-09)
      Introduction South Africa is a country known for its high levels of HIV infection and sexual violence. Although the interface between gender-based violence, HIV and mental health has been described, there are substantial gaps ...
    • A survey of participants in two internet support groups for people with hair-pulling 

      Bruwer, Belinda R.; Stein, Dan J. (BMC Psychiatry, 2005-10)
      Background: A substantial number of patients suffering from psychological problems or psychiatric disorders have turned to internet support groups for help. This paper reports on the perceived effectiveness of trichotillomania ...
    • Symmetry symptoms in obsessive-compulsive disorder : clinical and genetic correlates 

      Lochner, Christine; McGregor, Nathaniel; Hemmings, Sian M. J.; Harvey, Brian H.; Breet, Elsie; Swanevelder, Sonja; Stein, Dan J. (Associacao Brasileira de Psiquiatria, 2016)
      Objective: In obsessive-compulsive disorder (OCD), symmetry-related symptoms may be important. Although clinical correlates of symmetry-related symptoms have been identified in OCD, few data exist on genetic associations. ...
    • To what extent does South African mental health and substance abuse research address priority issues? 

      Flisher, Alan J.; Parry, Charles D. H.; Stein, Dan J. (Health & Medical Publishing Group, 2000-04)
      Objective. To investigate the extent to which South African mental health research addresses priority issues. Design. Cross-sectional survey of conference presentations. Setting. The most recent conferences of the following ...
    • Tobacco use and nicotine dependence among people living with HIV who drink heavily in South Africa : a cross-sectional baseline study 

      Egbe, Catherine O.; Londani, Mukhethwa; Parry, Charles D. H.; Myers, Bronwyn; Shuper, Paul A.; Nkosi, Sebenzile; Morojele, Neo K. (BMC (part of Springer Nature), 2019-12-16)
      Background: People living with HIV (PLWH) who drink alcohol and use tobacco are particularly vulnerable to tobacco-induced diseases due to an already compromised immune system. This study investigated the prevalence and ...
    • A total ban on alcohol advertising : presenting the public health case 

      Parry, Charles; Burnhams, Nadine Harker; London, Leslie (Health and Medical Publishing Group (HMPG), 2012-06)
      Evidence from burden of disease and economic costing studies amply indicate that the public health burden from hazardous and harmful use of alcohol in South Africa warrants drastic action. Evidence that banning alcohol ...
    • Toward identifying reproducible brain signatures of obsessive-compulsive profiles : rationale and methods for a new global initiative 

      Simpson, Helen Blair; Van Den Heuvel, Odile A.; Miguel, Euripedes C.; Reddy, Y. C. J.; Stein, Dan J.; Lewis-Fernandez, Roberto; Shavitt, Roseli Gedanke; Lochner, Christine; Pouwels, Petra J. W.; Narayanawamy, Janardhanan C.; Venkatasubramanian, Ganesan; Hezel, Dianne M.; Vriend, Chris; Batistuzzo, Marcelo C.; Hoexter, Marcelo Q.; De Joode, Niels T.; Costa, Daniel Lucas; De Mathis, Maria Alice; Sheshachala, Karthik; Narayan, Madhuri; Van Balkom, Anton J. L. M.; Batelaan, Neeltje M.; Venkataram, Shivakumar; Cherian, Anish; Marincowitz, Clara; Pannekoek, Nienke; Stovezky, Yael R.; Mare, Karen; Liu, Feng; Otaduy, Maria Concepcion Garcia; Pastorello, Bruno; Rao, Rashmi; Katechis, Martha; Van Meter, Page; Wall, Melanie (BMC (part of Springer Nature), 2020-02-14)
      Background: Obsessive-compulsive disorder (OCD) has a lifetime prevalence of 2–3% and is a leading cause of global disability. Brain circuit abnormalities in individuals with OCD have been identified, but important knowledge ...
    • Trauma exposure, posttraumatic stress disorder and the effect of explanatory variables in paramedic trainees 

      Fjeldheim, Celine B.; Nothling, Jani; Pretorius, Karin; Basson, Marina; Ganasen, Keith; Heneke, Robin; Cloete, Karen J.; Seedat, Soraya (BioMed Central, 2014-04)
      Abstract Background: Emergency healthcare workers, including trainees and individuals in related occupations are at heightened risk of developing posttraumatic stress disorder (PTSD) and depression owing to work-related ...
    • The treatment of alcohol dependence : new horizons 

      Pienaar, Willie (Health & Medical Publishing Group, 2004-04)
      No abstract available.
    • Understanding the impact of hazardous and harmful use of alcohol and/or other drugs on ARV adherence and disease progression 

      Kader, Rehana; Govender, Rajen; Seedat, Soraya; Koch, John Randy; Parry, Charles (Public Library of Science, 2015-05)
      The objective of this study was to understand the impact of hazardous and harmful use of alcohol and/or other drugs on ARV adherence and disease progression among HIV patients. A cross-sectional study design was used. A ...
    • Undiagnosed metabolic syndrome and other adverse effects among clozapine users of Xhosa descent 

      Faasen, N.; Niehaus, Dana J. H.; Koen, L.; Jordaan, E. (AOSIS Publishing, 2014-07)
      Background. Clozapine use is known to be associated with significant side-effects, including prolongation of the QT-interval, agranulocytosis and metabolic syndrome. However, few data exist on the prevalence of clozapine ...