• Obsessive compulsive disorder 

      Stein, D. J. (AOSIS, 2013)
      This guideline focuses on the pharmacotherapy of obsessivecompulsive disorder (OCD). OCD is characterised by obsessions and compulsions. A number of other disorders are also characterised by repetitive thoughts and rituals ...
    • Obsessive compulsive disorder : prevalence in Xhosa-speaking schizophrenia patients 

      Niehaus, D. J. H.; Koen, L.; Muller, J.; Laurent, C.; Stein, D. J.; Lochner, C.; Seedat, S.; Mbanga, I.; Deleuze, J.-F.; Mallet, J.; Emsley, R. A. (Health & Medical Publishing Group, 2005)
      Obsessive compulsive disorder (OCD) has been reported in up to 31% of schizophrenia sufferers. This study evaluated the presence of OCD in a Xhosa-speaking schizophrenia group. Xhosa patients (N = 509, including 100 sibships) ...
    • Obsessive-compulsive disorder and trichotillomania : a phenomenological comparison 

      Lochner, Christine; Seedat, Soraya; Du Toit, Pieter L.; Nel, Daniel G.; Niehaus, Dana J. H.; Sandler, Robin; Stein, Dan J. (BioMed Central, 2005-01)
      Background: Similarities between obsessive-compulsive disorder (OCD) and trichotillomania (TTM) have been widely recognized. Nevertheless, there is evidence of important differences between these two disorders. Some authors ...
    • Obsessive-compulsive disorder in black South Africans - A case series 

      Gangdev, P. S.; Stein, D. J.; Ruzibiza, J. B. (Health & Medical Publishing Group, 1996)
      Background. Obsessive-compulsive disorder (OCD) has been shown to be highly prevalent in both developing and developed countries. Nevertheless, data on OCD in blacks, and black South Africans in particular, are limited. ...
    • Occupation and schizophrenia in a Xhosa population - A variant of the social drift theory? 

      Brink, Sandra; Niehaus, Dana J. H.; Oosthuizen, Piet; Muller, Jacqueline; Koen, Liezl (Health & Medical Publishing Group, 2004)
      ENGLISH SUMMARY : no abstract available.
    • Olfactory reference syndrome in DSM-V 

      Flegar, S. J.; Vythilingum, B.; Stein, D. J.; Lochner, C. (Health and Medical Publishing Group (HMPG), 2009-09)
      To the Editor: We read with interest Dr A Lawrence’s recent SAMJ case report of a young man who presented with persistent preoccupation with personal body odour in the absence of any physical abnormalities
    • Once-monthly paliperidone palmitate in early stage schizophrenia – a retrospective, non-interventional 1-year study of patients with newly diagnosed schizophrenia 

      Emsley, Robin A.; Hargarter, Ludger; Bergmans, Paul; Uglesic, Boran; Sengul, Abdullah Cem; Petralia, Antonino; Khannanova, Angelina; Cherubin, Pierre; Schreiner, Andreas (Dove Medical Press, 2017)
      Background: Long-acting antipsychotic therapy may be best suited for patients in the early stage of schizophrenia, when the most can be done before disease progression associated with poor adherence occurs. We explored the ...
    • Outcomes of adult heroin users v. abstinent users four years after presenting for heroin detoxification treatment 

      Khan, Zureida; Cloete, Karen Jacqueline; Harvey, Justin; Weich, Lize (AOSIS Publishing, 2014-08)
      Background. There are no studies in South Africa (SA) on the outcomes following detoxification and psychosocial rehabilitation of heroindependent patients. Objective. To compare the demographic, clinical, forensic and ...
    • Participants’ perspectives of weekly telephonic mood monitoring in South Africa : a feasibility study 

      Van der Watt, A. S. J.; Roos, T.; Beyer, C.; Seedat, S. (BioMed Central, 2018-02-22)
      Background: Mood and anxiety disorders have a high lifetime prevalence, and their chronicity adds to the management burden of already scarce and strained mental health care resources, particularly in developing countries. ...
    • Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture 

      Davis, Lea K.; Yu, Dongmei; Keenan, Clare L.; Gamazon, Eric R.; Konkashbaev, Anuar I.; Derks, Eske M.; Neale, Benjamin M.; Yang, Jian; Lee, S. Hong; Evans, Patrick; Barr, Cathy L.; Bellodi, Laura; Benarroch, Fortu; Berrio, Gabriel Bedoya; Bienvenu, Oscar J.; Bloch, Michael H.; Blom, Rianne M.; Bruun, Ruth D.; Budman, Cathy L.; Camarena, Beatriz; Campbell, Desmond; Cappi, Carolina; Silgado, Julio C. Cardona; Cath, Danielle C.; Cavallini, Maria C.; Chavira, Denise A.; Chouinard, Sylvain; Conti, David. V.; Cook, Edwin H.; Coric, Vladimir; Cullen, Bernadette A.; Deforce, Dieter; Delorme, Richard; Dion, Yves; Edlund, Christopher K.; Egberts, Karin; Falkai, Peter; Fernandez, Thomas V.; Gallagher, Patience J.; Garrido, Helena; Geller, Daniel; Girard, Simon L.; Grabe, Hans J.; Grados, Marco A.; Greenberg, Benjamin D.; Gross-Tsur, Varda; Haddad, Stephen; Heiman, Gary A.; Hemmings, Sian M. J.; Hounie, Ana G.; Illmann, Cornelia; Jankovic, Joseph; Jenike, Michael A.; Kennedy, James L.; King, Robert A.; Kremeyer, Barbara; Kurlan, Roger; Lanzagorta, Nuria; Leboyer, Marion; Leckman, James F.; Lennertz, Leonhard; Liu, Chunyu; Lochner, Christine; Lowe, Thomas L.; Macciardi, Fabio; McCracken, James T.; McGrath, Lauren M.; Mesa Restrepo, Sandra C.; Moessner, Rainald; Morgan, Jubel; Muller, Heike; Murphy, Dennis L.; Naarden, Allan L.; Ochoa, William Cornejo; Ophoff, Roel A.; Osiecki, Lisa; Pakstis, Andrew J.; Pato, Michele T.; Pato, Carlos N.; Piacentini, John; Pittenger, Christopher; Pollak, Yehuda; Rauch, Scott L.; Renner, Tobias J.; Reus, Victor I.; Richter, Margaret A.; Riddle, Mark A.; Robertson, Mary M.; Romero, Roxana; Rosario, Maria C.; Rosenberg, David; Rouleau, Guy A.; Ruhrmann, Stephan; Ruiz-Linares, Andres; Sampaio, Aline S.; Samuels, Jack; Sandor, Paul; Sheppard, Brooke; Singer, Harvey S.; Smit, Jan H.; Stein, Dan J.; Strengman, E.; Tischfield, Jay A.; Valencia Duarte, Ana V.; Vallada, Homero; Van Nieuwerburgh, Filip; Veenstra-VanderWeele, Jeremy; Walitza, Susanne; Wang, Ying; Wendland, Jens R.; Westenberg, Herman G. M.; Shugart, Yin Yao; Miguel, Euripedes C.; McMahon, William; Wagner, Michael; Nicolini, Humberto; Posthuma, Danielle; Hanna, Gregory L.; Heutnik, Peter; Denys, Damiaan; Arnold, Paul D.; Oostra, Ben A.; Nestadt, Gerald; Freimer, Nelson B.; Pauls, David L.; Wray, Naomi R.; Stewart, S. Evelyn; Mathews, Carol A.; Knowles, James A.; Cox, Nancy J.; Shcarf, Jeremiah M. (PLoS, 2013-10)
      The direct estimation of heritability from genome-wide common variant data as implemented in the program Genome-wide Complex Trait Analysis (GCTA) has provided a means to quantify heritability attributable to all interrogated ...
    • Patterns of substance use in South Africa : results from the South African Stress and Health study 

      Van Heerden, Margaretha S.; Grimsrud, Anna T.; Seedat, Soraya; Myer, Landon; Williams, David R.; Stein, Dan J. (Health and Medical Publishing Group (HMPG), 2009)
      Background. There are limited data on substance use in South Africa. We describe patterns of substance use based on recent, nationally representative data. Methods. Data were derived from the 2002-2004 South African Stress ...
    • Perceived discrimination and mental health disorders : the South African Stress and Health study (SASH) 

      Moomal, Hashim; Jackson, Pamela B.; Stein, Dan J.; Herman, Allen; Myer, Landon; Seedat, Soraya; Madela-Mntla, Edith; Williams, D. R. (Health and Medical Publishing Group (HMPG), 2009)
      Objectives. To describe the demographic correlates of perceived discrimination and explore the association between perceived discrimination and psychiatric disorders. Design. A national household survey was conducted between ...
    • Perceptions of alcohol use in the context of HIV treatment : a qualitative study 

      Madhombiro, Munyaradzi; Marimbe-Dube, Bazondlile; Dube, Michelle; Kaiyo-Utete, Malinda; Paradzai, Angeline; Chibanda, Dixon; Rusakaniko, Simbarashe; Van Der Watt, A. S. J.; Seedat, Soraya (Dove Medical Press, 2018)
      Background: Alcohol use is associated with poor HIV treatment outcomes. This study aimed to understand patients’ perceptions of the impact of alcohol use in the context of HIV care. Methods: The study design was a descriptive ...
    • Perpetration of gross human rights violations in South Africa : association with psychiatric disorders 

      Stein, Dan J.; Williams, Stacey L.; Jackson, Pamela B.; Seedat, Soraya; Myer, Landon; Herman, Allen; Williams, David R. (Health and Medical Publishing Group (HMPG), 2009)
      Background. A nationally representative study of psychiatric disorders in South Africa provided an opportunity to study the association between perpetration of human rights violations (HRVs) during apartheid and psychiatric ...
    • Pharmacological challenge with a serotonin 1D agonist in alcohol dependence 

      Vythilingum, Bavanisha; Hugo, Charmaine J.; Maritz, J. Stefan; Pienaar, Willie P.; Stein, Dan J. (BioMed Central, 2005-08)
      Background: Both animal and clinical studies have implicated serotonergic dysfunction in the pathogenesis of alcohol abuse and dependence. However the exact mechanisms involved remain unknown. Theoretically, low serotonin ...
    • Pharmacotherapy for post-traumatic stress disorder : a systematic review and meta-analysis 

      Ipser, Jonathan; Seedat, Soraya; Stein, Dan J. (Health & Medical Publishing Group, 2006-10)
      Background. Post-traumatic stress disorder (PTSD) is a prevalent and disabling condition. Evidence that PTSD is characterised by specific psychobiological dysfunctions has contributed to a growing interest in use of ...
    • Pica and the obsessive-compulsive spectrum disorders 

      Stein, D. J.; Bouwer, C.; Van Heerden, B. (Health & Medical Publishing Group, 1996)
      Background. The concept of a spectrum of obsessive-compulsive related disorders may have clinical and research heuristic value in the approach to disorders similar to obsessive-compulsive disorder (OCD) in respect of ...
    • A pilot and feasibility randomised controlled study of prolonged exposure treatment and supportive counselling for post-traumatic stress disorder in adolescents : a third world, task-shifting, community-based sample 

      Rossouw, Jaco; Yadin, Elna; Alexander, Debra; Mbanga, Irene; Jacobs, Tracy; Seedat, Soraya (BioMed Central, 2016-11-17)
      ENGLISH SUMMARY : Background: There is a dearth of empirical evidence on the effectiveness of pharmacological and nonpharmacological treatments for adolescents with post-traumatic stress disorder (PTSD) in developing country ...
    • Placebo controls in clinical trials : concerns about use in relapse prevention studies in schizophrenia 

      Emsley, Robin A.; Turoff, Sarah; Fleischhacker, W. Wolfgang; Galderisi, Silvana; Halpern, Lisa J.; McEvoy, Joseph P.; Schooler, Nina R. (BMJ Publishing Group, 2016)
      ENGLISH SUMMARY : The use of placebos in clinical trials has major policy implications for ethical conduct across all of medicine and is relevant to clinicians, patients, drug development, and regulatory agencies. This ...
    • Post-menopausal panic disorder 

      Stein, D. J.; Bouwer, C. (Health & Medical Publishing Group, 1996)
      [No abstract available]