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Prioritization of candidate genes for a South African family with Parkinson’s disease using in-silico tools
(Public Library of Science, 2021)Parkinson’s disease (PD) is a neurodegenerative disorder exhibiting Mendelian inheritance in some families. Next-generation sequencing approaches, including whole exome sequencing (WES), have revolutionized the field of ... -
Novel molecular transport medium used in combination with Xpert MTB/RIF ultra provides rapid detection of Mycobacterium bovis in African buffaloes
(Nature Research (part of Springer Nature), 2021)ENGLISH ABSTRACT: Mycobacterium bovis is the causative agent of bovine tuberculosis (bTB) in wildlife. Confirmation of M. bovis infection relies on mycobacterial culture, which is time-consuming. Collection and transportation ... -
High diversity, inbreeding and a dynamic Pleistocene demographic history revealed by African buffalo genomes
(Nature Research (part of Springer Nature), 2021)Genomes retain records of demographic changes and evolutionary forces that shape species and populations. Remnant populations of African buffalo (Syncerus caffer) in South Africa, with varied histories, provide an opportunity ...
