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Now showing items 1-2 of 2

    • Mechanisms of drug-induced tolerance in mycobacterium tuberculosis 

      Goossens, Sander N.; Sampson, Samantha L.; van Rie, Annelies (American Society for Microbiology, 2020-10)
      Successful treatment of tuberculosis (TB) can be hampered by Mycobacterium tuberculosis populations that are temporarily able to survive antibiotic pressure in the absence of drug resistance-conferring mutations, a phenomenon ...

    • Immune profiling enables stratification of patients with active tuberculosis disease or mycobacterium tuberculosis infection 

      Duffy, Darragh; Nemes, Elisa; Llibre, Alba; Rouilly, Vincent; Musvosvi, Munyaradzi; Smith, Nikaïa; Filander, Elizabeth; Africa, Hadn; Mabwe, Simbarashe; Jaxa, Lungisa; Charbit, Bruno; Mulenga, Humphrey; Tameris, Michele; Walzl, Gerhard; Malherbe, Stephanus; Thomas, Stephanie; Hatherill, Mark; Bilek, Nicole; Scriba, Thomas J.; Albert, Matthew L. (Oxford University Press, 2020-10)
      Background Tuberculosis (TB) is caused by Mycobacterium tuberculosis (Mtb) infection and is a major public health problem. Clinical challenges include the lack of a blood-based test for active disease. Current blood-based ...