Drug-resistant tuberculosis transmission and resistance amplification within families

Date
2012
Authors
Seddon J.A.
Warren R.M.
Enarson D.A.
Beyers N.
Simon Schaaf H.
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Abstract
Drug-resistant tuberculosis is caused by transmission of resistant strains of Mycobacterium tuberculosis and by acquisition of resistance through inadequate treatment. We investigated the clinical and molecular features of the disease in 2 families after drug-resistant tuberculosis was identified in 2 children. The findings demonstrate the potential for resistance to be transmitted and amplified within families.
Description
Article
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Citation
Emerging Infectious Diseases
18
8
1342
1345