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    Biocatalytic preparation and characterization of alternative substrate of MshB, a mycothiol pathway enzyme 

    Muneri, Ndivhuwo Olga (Stellenbosch : Stellenbosch University, 2012-12)
    ENGLISH ABSTRACT: Mycobacterium tuberculosis (M. tuberculosis), the causative agent of tuberculosis, utilizes mycothiol (MSH) as the major low molecular weight thiol to protect itself against oxidative stress and thereby ...
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    Characterization of natural antimicrobial peptides adsorbed to different matrices 

    van Rensburg, Wilma (Stellenbosch : Stellenbosch University, 2015-12)
    ENGLISH ABSTRACT: Biofouling is the attachment and biofilm formation that leads to negative repercussions such as persistent post-harvest infections, infections obtained from medical implants and continual surface ...
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    The inhibitory effect of rooibos on cytochromes P450 and downstream in vitro modulation of steroid hormones 

    Mugari, Mufaro Buhlebenkosi (Stellenbosch : Stellenbosch University, 2015-04)
    ENGLISH ABSTRACT: This study describes: 1. Substrate binding assays investigating the effects of methanolic extracts of unfermented and fermented Rooibos on the binding of natural substrates to ovine adrenal microsomal ...
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    Organic codes and their identification : is the histone code a true organic code 

    Kühn, Stefan (Stellenbosch : Stellenbosch University, 2014-03)
    ENGLISH ABSTRACT: Codes are ubiquitous in culture|and, by implication, in nature. Code biology is the study of these codes. However, the term `code' has assumed a variety of meanings, sowing confusion and cynicism. The ...
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    Partial characterization of a bacterial acyltransferase enzyme for potential application in dairy processing 

    Hayward, Stefan (Stellenbosch : Stellenbosch University, 2014-04)
    ENGLISH ABSTRACT: This study describes: the evaluation of the current, and potential assay methods for the quantification of cholesterol, cholesteryl esters and free fatty acids in milk and the application thereof ; ...
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    Isolation and identification of compounds conferring phytoestrogenic activity to Cyclopia extracts 

    Mortimer, Morne Francois (Stellenbosch : Stellenbosch University, 2014-12)
    ENGLISH ABSTRACT: Phytoestrogens are perceived as a safer alternative to conventional hormone replacement therapy (HRT) for the alleviation of menopausal symptoms as they present a decreased side-effect profile. The Cyclopia ...
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    Towards a kinetic model of the Entner-Doudoroff pathway in Zymomonas mobilis 

    Van Staden, Charles Theo (Stellenbosch : Stellenbosch University, 2014-12)
    ENGLISH ABSTRACT: Metabolic networks of cellular systems are complex, in that there are numerous components with multiple non-linear interactions. To understand how these networks work they are often split into manageable ...
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    Investigating self-fabrication in the context of artificial chemistries 

    Van Niekerk, Christopher (Stellenbosch : Stellenbosch University, 2014-12)
    ENGLISH ABSTRACT: This thesis gives a broad overview of what artificial chemistries (ACs) are, a brief review of several ACs and their applications, and an in depth analysis of one speci c AC: the four-bit binary string ...
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    Comparison of progress curve analysis and initial rate kinetics for the estimation of identifiable enzyme kinetic parameters : a case study using two glycolytic enzymes from Sulfolobus solfataricus 

    Louw, Carla (Stellenbosch : Stellenbosch University, 2016-12)
    ENGLISH ABSTRACT: Obtaining accurate parameter value estimations is imperative to studying enzyme kinetics. It is also important that these parameter values be identifiable. The nonidentifiability of parameter estimations ...
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    The characterisation of the catalytic activity of human steroid 5α-reductase towards novel C19 substrates 

    Quanson, Jonathan Luke (Stellenbosch : Stellenbosch University, 2015-02-25)
    ENGLISH ABSTRACT: This study describes: • The UPLC-MS/MS analyses and quantification of novel 5α-reduced steroids using response factors. • The kinetic characterisation of human steroid 5α-reductase type 1 (SRD5A1), expressed ...
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    AuthorAdams, Waldo Wayne (1)Allie, Fatima (1)Anderson, Chanelle (1)Appel, Maryke (1)Arends, Arrie Paul (1)Badenhorst, Melinda (1)Barnard, Lise (1)Barnard, Monique (1)Barry, Christopher James (1)Berge, Simon Nicholas (1)... View MoreSubject
    UCTD (86)
    Dissertations -- Biochemistry (8)Saccharomyces cerevisiae (7)Theses -- Biochemistry (5)Enzyme kinetics (4)Glycolysis (4)Insulin resistance (4)Insulin signalling (4)Prostate -- Cancer (4)Androgen receptor (3)... View MoreDate Issued2020 - 2022 (26)2010 - 2019 (57)1996 - 1999 (3)Has File(s)Yes (86)
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