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Biocatalytic preparation and characterization of alternative substrate of MshB, a mycothiol pathway enzyme
(Stellenbosch : Stellenbosch University, 2012-12)
ENGLISH ABSTRACT: Mycobacterium tuberculosis (M. tuberculosis), the causative agent of tuberculosis,
utilizes mycothiol (MSH) as the major low molecular weight thiol to protect itself
against oxidative stress and thereby ...
Characterization of natural antimicrobial peptides adsorbed to different matrices
(Stellenbosch : Stellenbosch University, 2015-12)
ENGLISH ABSTRACT: Biofouling is the attachment and biofilm formation that leads to negative repercussions such as
persistent post-harvest infections, infections obtained from medical implants and continual
surface ...
Glycerol production in plasmodium falciparum : towards a detailed kinetic model
(Stellenbosch : Stellenbosch University, 2015-02-24)
ENGLISH ABSTRACT: Having caused the deaths of more than 10 million individuals since 2000 with
most of them occurring in Africa, malaria remains a serious disease that requires
undivided attention. To this end a detailed ...
The inhibitory effect of rooibos on cytochromes P450 and downstream in vitro modulation of steroid hormones
(Stellenbosch : Stellenbosch University, 2015-04)
ENGLISH ABSTRACT: This study describes:
1. Substrate binding assays investigating the effects of methanolic extracts of
unfermented and fermented Rooibos on the binding of natural substrates to ovine
adrenal microsomal ...
Organic codes and their identification : is the histone code a true organic code
(Stellenbosch : Stellenbosch University, 2014-03)
ENGLISH ABSTRACT: Codes are ubiquitous in culture|and, by implication, in nature. Code
biology is the study of these codes. However, the term `code' has assumed
a variety of meanings, sowing confusion and cynicism. The ...
Partial characterization of a bacterial acyltransferase enzyme for potential application in dairy processing
(Stellenbosch : Stellenbosch University, 2014-04)
ENGLISH ABSTRACT: This study describes:
the evaluation of the current, and potential assay methods for the quantification of cholesterol, cholesteryl esters and free fatty acids in milk and the application thereof ;
...
Isolation and identification of compounds conferring phytoestrogenic activity to Cyclopia extracts
(Stellenbosch : Stellenbosch University, 2014-12)
ENGLISH ABSTRACT: Phytoestrogens are perceived as a safer alternative to conventional hormone replacement therapy (HRT) for the alleviation of menopausal symptoms as they present a decreased side-effect profile. The Cyclopia ...
Towards a kinetic model of the Entner-Doudoroff pathway in Zymomonas mobilis
(Stellenbosch : Stellenbosch University, 2014-12)
ENGLISH ABSTRACT: Metabolic networks of cellular systems are complex, in that there are numerous components with
multiple non-linear interactions. To understand how these networks work they are often split into
manageable ...
Investigating self-fabrication in the context of artificial chemistries
(Stellenbosch : Stellenbosch University, 2014-12)
ENGLISH ABSTRACT: This thesis gives a broad overview of what artificial chemistries (ACs) are, a
brief review of several ACs and their applications, and an in depth analysis
of one speci c AC: the four-bit binary string ...
Comparison of progress curve analysis and initial rate kinetics for the estimation of identifiable enzyme kinetic parameters : a case study using two glycolytic enzymes from Sulfolobus solfataricus
(Stellenbosch : Stellenbosch University, 2016-12)
ENGLISH ABSTRACT: Obtaining accurate parameter value estimations is imperative to studying enzyme kinetics.
It is also important that these parameter values be identifiable. The nonidentifiability
of parameter estimations ...