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Experimental supply demand analysis of yeast fermentative free energy metabolism : an in vivo and in situ investigation
(Stellenbosch : University of Stellenbosch, 2010-12)
Please refer to full text for abstract
A systematic investigation into the quantitative effect of pH changes on the upper glycolytic enzymes of Escherichia coli and Saccharomyces cerevisiae
(Stellenbosch : Stellenbosch University, 2018-03)
ENGLISH ABSTRACT: Kinetic modelling of biological phenomena in an attempt to understand the underlying
dynamics and complexity of life is becoming an indispensable tool to systems
biology. A new paradigm of mathematical ...
Investigating the dynamics of hydrogen peroxide metabolism in the peroxiredoxin system of Saccharomyces cerevisiae
(Stellenbosch : Stellenbosch University, 2020-03)
ENGLISH ABSTRACT: Reactive oxygen species (ROS) are derivations of molecular oxygen that can have detrimental e ects in cells. ROS can readily react with DNA, proteins and lipids often resulting in the loss of structure ...
An investigation into the effects of macromolecular crowding on the kinetics of upper glycolytic enzymes in Saccharomyces cerevisiae
(Stellenbosch : Stellenbosch University, 2020-03)
ENGLISH ABSTRACT: In order for mathematical models of metabolism to accurately emulate experimental data the conditions in which parameter values are obtained must be close to the actual in vivo environment. However, this ...
The effect of adenylate kinase on the glycolytic oscillations of Saccharomyces cerevisiae
(Stellenbosch : Stellenbosch University, 2019-03)
ENGLISH ABSTRACT: The regulation of phosphofructokinase (PFK) by ATP and AMP is a necessary
feature for glycolytic oscillations. The enzyme adenylate kinase (AK) is responsible for the interconversion of ATP + AMP 2 ...
A bioinformatics tool to detect physical gene clusters in functional genomics data
(Stellenbosch : Stellenbosch University, 2021-03)
ENGLISH ABSTRACT: Many studies have investigated the biological effects of the external environment on the genetic expression of a living cell. This particular study looks at gene clusters that are switched on at a series ...
Effect of yeasts and oenological parameters on acetaldehyde production during alcoholic fermentation of South African grape musts
(Stellenbosch : Stellenbosch University, 2020-03)
ENGLISH ABSTRACT: Acetaldehyde plays a role in the rate of fermentation and the quality of wine. High levels
of acetaldehyde in fermenting juice may result in sluggish/stuck fermentations, and in
wine, it may impart ...
Supply-demand analysis of anaerobic free-energy metabolism in Saccharomyces cerevisiae
(Stellenbosch : Stellenbosch University, 2003-12)
ENGLISH ABSTRACT: Scientists and biochemical engineers alike are very interested in the control and regulation
of free-energy metabolism in micro-organisms, whether the findings purely
satisfy scientific curiosity or ...
Testing Monod : growth rate as a function of glucose concentration in Saccharomyces cerevisiae
(Stellenbosch : University of Stellenbosch, 2004-12)
ENGLISH ABSTRACT: The complexity of microbial systems has presented serious obstacles to the quantification of
fermentation processes. Using computer modelling techniques progress has been made in
monitoring, controlling ...