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Mathematical modelling of hypoglycaemia and lactic acidosis in the bloodstream of Plasmodium berghei infected rats: a feasibility study
(Stellenbosch : Stellenbosch University, 2016-03)
ENGLISH ABSTRACT : Needless prescription and overuse of anti-microbial compounds served as a catalyst
for the evolution and rise of multiple drug resistant pathogens, one of humanities
greatest threats in the anti-biotic ...
Glycolytic flux control of glyceraldehyde 3-phosphate dehydrogenase in yeast
(Stellenbosch : Stellenbosch University, 2019-12)
ENGLISH ABSTRACT: To save precious experimental time and resources and to gain a deeper understanding of living systems, modelling approaches and systems biological tools like Metabolic Control Analysis (MCA) offer the ...
Mathematical modelling of glycolysis in cancer cell lines
(Stellenbosch : Stellenbosch University, 2021-03)
ENGLISH ABSTRACT: Most cancer cells exhibit an increase in glucose uptake and lactate produc- tion, a
phenomenon known as the "Warburg effect" or aerobic glycolysis, and considered to be a hallmark of
cancer ...
Construction and validation of a detailed kinetic model of glycolysis in asexual Plasmodium falciparum : a feasibility study
(Stellenbosch : University of Stellenbosch, 2009-12)
ENGLISH ABSTRACT:
In Africa alone, Plasmodium, the causative agent of malaria is estimated to kill
a child, under the age of five every thirty seconds140. The ability of the parasite
to rapidly attain resistance, has ...
Glycerol production in plasmodium falciparum : towards a detailed kinetic model
(Stellenbosch : Stellenbosch University, 2015-02-24)
ENGLISH ABSTRACT: Having caused the deaths of more than 10 million individuals since 2000 with
most of them occurring in Africa, malaria remains a serious disease that requires
undivided attention. To this end a detailed ...