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Functional analysis and recombinant expression of a sea urchin G-string binding factor
(Stellenbosch : Stellenbosch University, 2001-12)
ENGLISH ABSTRACT: The sea urchin G-string binding factor 1 (suGF1) has previously been shown to bind with
high affinity and selectivity to stretches of contiguous deoxyguanosine residues, a DNA
motif found in the upstream ...
Investigating the mechanism of transcriptional regulation of the gonadotropin-releasing hormone receptor (GnRHR) gene by dexamethasone
(Stellenbosch : Stellenbosch University, 2008-12)
Gonadotropin-releasing hormone (GnRH) acting through the cognate GnRH receptor (GnRH-R)
plays an important role in the regulation of mammalian reproductive function by regulating the
synthesis and release of follicle ...
The role of steroidogenic factor-1 (SF-1) in transcriptional regulation of the gonadotropin-releasing hormone (GnRH) receptor gene
(Stellenbosch : Stellenbosch University, 2001-03)
ENGLISH ABSTRACT: The GnRH receptor is a G-protein-coupled receptor in pituitary gonadotrope
cells. Binding of its ligand, GnRH, results in synthesis and release of
gonadotropin hormones luteinizing hormone (LH) and ...
Interaction of SF-1 and Nur77 proteins from a gonadotrope cell line with the promoter of the GnRH receptor gene : implications for gene regulation
(Stellenbosch : Stellenbosch University, 2001-12)
ENGLISH ABSTRACT: The regulation of gonadotropin releasing hormone (GnRH) receptor numbers in the pituitary is a
crucial control point in reproduction. Pituitary sensitivity to GnRH can be directly correlated with
GnRH ...