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Towards a kinetic model of the Entner-Doudoroff pathway in Zymomonas mobilis
(Stellenbosch : Stellenbosch University, 2014-12)
ENGLISH ABSTRACT: Metabolic networks of cellular systems are complex, in that there are numerous components with
multiple non-linear interactions. To understand how these networks work they are often split into
manageable ...
Comparison of progress curve analysis and initial rate kinetics for the estimation of identifiable enzyme kinetic parameters : a case study using two glycolytic enzymes from Sulfolobus solfataricus
(Stellenbosch : Stellenbosch University, 2016-12)
ENGLISH ABSTRACT: Obtaining accurate parameter value estimations is imperative to studying enzyme kinetics.
It is also important that these parameter values be identifiable. The nonidentifiability
of parameter estimations ...
A generic rate equation for catalysed, template-directed polymerisation and its use in computational systems biology
(Stellenbosch : Stellenbosch University, 2011-12)
ENGLISH ABSTRACT: Progress in computational systems biology depends crucially on the availability
of generic rate equations that accurately describe the behaviour
and regulation of catalysed processes over a wide range ...
An investigation into the effects of macromolecular crowding on the kinetics of upper glycolytic enzymes in Saccharomyces cerevisiae
(Stellenbosch : Stellenbosch University, 2020-03)
ENGLISH ABSTRACT: In order for mathematical models of metabolism to accurately emulate experimental data the conditions in which parameter values are obtained must be close to the actual in vivo environment. However, this ...