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Biocatalytic preparation and characterization of alternative substrate of MshB, a mycothiol pathway enzyme
(Stellenbosch : Stellenbosch University, 2012-12)
ENGLISH ABSTRACT: Mycobacterium tuberculosis (M. tuberculosis), the causative agent of tuberculosis,
utilizes mycothiol (MSH) as the major low molecular weight thiol to protect itself
against oxidative stress and thereby ...
Laboratory optimization of a protease extraction and purification process from bovine pancreas in preparation for industrial scale up
(Stellenbosch : Stellenbosch University, 2012-12)
ENGLISH ABSTRACT: This study describes:
a) Characterization of traditional methodologies and testing methods used to purify and quantify trypsin and α-chymotrypsin
b) Re-engineering / development of a new method for ...
The optimization of the extraction and purification of horseradish peroxidase from horseradish roots
(Stellenbosch : Stellenbosch University, 2012-12)
ENGLISH ABSTRACT: This study describes:
a) the optimization of the current industrial-scale extraction and purification of Horseradish
peroxidase from horseradish at BBI Enzymes, focussing on:
a. Raw material quality,
b. ...
Characterization of natural antimicrobial peptides adsorbed to different matrices
(Stellenbosch : Stellenbosch University, 2015-12)
ENGLISH ABSTRACT: Biofouling is the attachment and biofilm formation that leads to negative repercussions such as
persistent post-harvest infections, infections obtained from medical implants and continual
surface ...
The effect of modulators of inflammation on hepatic acute phase proteins and metabolic enzymes
(Stellenbosch : University of Stellenbosch, 2010-03)
ENGLISH ABSTRACT:
Crosstalk exists between the stress- and immune-system and this crosstalk has pharmacological
importance in the use of glucocorticoids (GCs) as anti-inflammatory drugs for diseases such as
asthma and ...
The inhibitory effect of rooibos on cytochromes P450 and downstream in vitro modulation of steroid hormones
(Stellenbosch : Stellenbosch University, 2015-04)
ENGLISH ABSTRACT: This study describes:
1. Substrate binding assays investigating the effects of methanolic extracts of
unfermented and fermented Rooibos on the binding of natural substrates to ovine
adrenal microsomal ...
Organic codes and their identification : is the histone code a true organic code
(Stellenbosch : Stellenbosch University, 2014-03)
ENGLISH ABSTRACT: Codes are ubiquitous in culture|and, by implication, in nature. Code
biology is the study of these codes. However, the term `code' has assumed
a variety of meanings, sowing confusion and cynicism. The ...
Partial characterization of a bacterial acyltransferase enzyme for potential application in dairy processing
(Stellenbosch : Stellenbosch University, 2014-04)
ENGLISH ABSTRACT: This study describes:
the evaluation of the current, and potential assay methods for the quantification of cholesterol, cholesteryl esters and free fatty acids in milk and the application thereof ;
...
Isolation and identification of compounds conferring phytoestrogenic activity to Cyclopia extracts
(Stellenbosch : Stellenbosch University, 2014-12)
ENGLISH ABSTRACT: Phytoestrogens are perceived as a safer alternative to conventional hormone replacement therapy (HRT) for the alleviation of menopausal symptoms as they present a decreased side-effect profile. The Cyclopia ...
Towards a kinetic model of the Entner-Doudoroff pathway in Zymomonas mobilis
(Stellenbosch : Stellenbosch University, 2014-12)
ENGLISH ABSTRACT: Metabolic networks of cellular systems are complex, in that there are numerous components with
multiple non-linear interactions. To understand how these networks work they are often split into
manageable ...