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    •   SUNScholar
    • Faculty of Science
    • Department of Biochemistry
    • Doctoral Degrees (Biochemistry)
    • Browsing by Issue Date
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        The metabolism of 11β-hydroxyandrostenedione by steroidogenic enzymes yields metabolites contributing to the androgen pool in prostate cancer 

        Du Toit, Therina (Stellenbosch : Stellenbosch University, 2018-03)
        ENGLISH ABSTRACT: This study describes: • The development and validation of three ultra-performance convergence chromatography tandem mass spectrometry (UPC2-MS/MS) analytical methods which were applied in the detection ...
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        Investigating the mechanism of action of hormones used in hormone replacement therapy via estrogen receptor subtypes and the influence of the progesterone receptor 

        Perkins, Meghan Samantha (Stellenbosch : Stellenbosch University, 2018-03)
        ENGLISH ABSTRACT: Estrogens and progestins used in conventional menopausal hormone therapy (HT) are associated with increased breast cancer risk. A diverse range of estrogens and progestins are available that mediate ...
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        Homologous down-regulation of the glucocorticoid receptor is influenced by the dimerization state of the receptor 

        Wilkinson, Legh (Stellenbosch : Stellenbosch University, 2018-03)
        ENGLISH ABSTRACT: Glucocorticoids (GCs) remain the mainstay therapeutic choice for the treatment of inflammation, and exert their potent anti-inflammatory effects via the glucocorticoid receptor (GRα). However, the chronic ...

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