Browsing Masters Degrees (Paediatrics and Child Health) by Title
Now showing items 1-20 of 48
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The aetiology of hypophosphatemia in children recovering from Kwashiorkor
(Stellenbosch : Stellenbosch University, 2015-12)ENGLISH ABSTRACT : Abstract Background The aetiology of hypophosphatemia in children recovering from kwashiorkor is poorly understood. Current theory of the pathophysiology of hypophosphatemia due to refeeding syndrome ... -
Central line-associated bloodstream infections in a resource-limited South African neonatal intensive care unit
(Stellenbosch : Stellenbosch University, 2016-12)ENGLISH SUMMARY: Background: The rate of central line-associated bloodstream infection (CLABSI) in South African public sector neonatal intensive care units (NICU) is unknown. Tygerberg Children’s Hospital (TCH) introduced ... -
Changes in cerebral blood flow and cardiac output in premature neonates in the first 72 hours of life
(Stellenbosch : Stellenbosch University, 2019-12)Background: A vital contributor of adverse neurodevelopmental outcome is the early acquisition of prematurity related brain injury associated with perturbations of cerebral haemodynamics. Several impediments ... -
Childhood tuberculous meningitis: a thirty year review of clinical and cerebrospinal fluid factors associated with bacteriological confirmation
(Stellenbosch : Stellenbosch University, 2017-12)ENGLISH ABSTRACT: Background: Tuberculous meningitis (TBM) is one of the most devastating complications of tuberculosis (TB)3 and contributes significantly to the morbidity and mortality of children in high burden TB ... -
Clinical characteristics and outcome of children evaluated and treated at Tygerberg Children’s Hospital during a measles epidemic
(Stellenbosch : Stellenbosch University, 2014-04)ENGLISH ABSTRACT: Objective: To describe the clinical characteristics and outcome of children presenting to Tygerberg Children’s Hospital with measles infection Methods: This was a retrospective, descriptive study of ... -
Clinical value of a uniform research case definition of tuberculous meningitis
(Stellenbosch : Stellenbosch University, 2014-04)ENGLISH ABSTRACT: BACKGROUND: Tuberculous meningitis (TBM) research remains important but obtaining adequate sample sizes of microbiologically-confirmed TBM cases is difficult, therefore clinical cases of TBM need to be ... -
CMV viral load as a predictor of the clinical course of CMV-associated pneumonia in hiv infected and uninfected infants
(Stellenbosch : Stellenbosch University, 2017-12)Background Lower respiratory tract infections is one of the leading causes of death in children under 5 years of age. In the advent of HIV, much of these lower respiratory tract infections are attributed to opportunistic ... -
Congenital rubella in the Western Cape Province of South Africa : a vaccine preventable condition
(Stellenbosch : Stellenbosch University, 2015-12)ENGLISH ABSTRACT : Background: Congenital rubella syndrome (CRS) is characterized by multiple defects causing physical, intellectual and developmental retardation, auditory and visual problems, placing a huge burden on ... -
The Correlation between hyponatremia and/or deranged cerebrospinal fluid glucose levels and the severity of childhood tuberculous meningitis
(Stellenbosch : Stellenbosch University, 2021-03)Introduction: Hyponatremia and/or hypoglycorrhachia are commonly encountered biochemical derangements during the acute stage of childhood tuberculous meningitis (TBM). Few studies have explored the correlation of the ... -
The correlation between the placental pathology and the neurological outcome of neonates ≥ 36 weeks with neonatal encephalopathy treated with therapeutic hypothermia
(Stellenbosch : Stellenbosch University, 2018-12)ENGLISH ABSTRACT: Introduction Perinatal asphyxia resulting in neonatal encephalopathy (NE) remains one of the commonest causes of death and morbidity in term infants in low and middle income countries. The cause of NE ... -
The cost effectiveness of treating paediatric cancer in South Africa: a review of treatment cost for Burkitt Lymphoma
(Stellenbosch : Stellenbosch University, 2016-12)ENGLISH SUMMARY: Background In middle and low income countries, childhood cancer is rare when compared to trauma and infectious diseases. There is a paucity of literature regarding the cost and cost-effectiveness of ... -
A cross sectional analysis of perinatally HIV-infected (PHIV) adolescents in a paediatric infectious diseases clinic in the Western Cape, South Africa
(Stellenbosch : Stellenbosch University, 2018-09)ENGLISH ABSTRACT: Background Approximately 1.8 million adolescents were living globally with HIV in 2015. HIV is the leading cause of death in adolescents in Africa and the second leading cause of death in adolescence ... -
Descriptive review of the health supervision received by children with Down syndrome at Worcester Provincial Hospital from 2010 to 2015
(Stellenbosch : Stellenbosch University, 2018-12)ENGLISH ABSTRACT: Background: In 2011, the American Academy of Paediatrics (AAP) published revised guidelines for health supervision of children with Down syndrome (DS). In the absence of South African guidelines, we ... -
Descriptive study evaluating the management and outcome of infants aged 21-90 days presenting to a paediatric emergency department with a possible serious bacterial infection
(2019-12)Background: Young infants with a possible serious bacterial infection (SBI) are a common presentation to paediatric emergency departments (PEDs). It is often difficult to distinguish clinically ... -
Diagnosis and outcome of primary solid thoracic tumours in a high tuberculosis prevalent setting
(2017-12)Background and aim Primary solid thoracic neoplasms (PSTT) have a diverse pathological spectrum, varying prognosis and survival rates and are unusual in children. Early recognition, diagnosis and treatment is key to a ... -
Does a serum C-Reactive Protein of less than 10mg/l predict the absence of Early Onset Neonatal Sepsis?
(Stellenbosch : Stellenbosch University, 2018-03)Abstract: The identification of early onset neonatal sepsis (EONS) remains a challenge. EONS carry a high case fatality. Balanced against this, the unnecessary use of antibiotics carries a high risk in neonates. It has ... -
Eating patterns of Indian preschool children between 1-5 years of age in Howick West (Kwa-Zulu Natal)
(Stellenbosch : Stellenbosch University, 2003-12)ENGLISH ABSTRACT: Most of the risk factors for coronary heart disease (CHD) such as hypertension, dyslipidaemia, smoking, non-insulin dependent diabetes mellitus (NIDDM), obesity, physical inactivity and heredity are ... -
The etiology and response to high dose oral prednisone in children with infantile spasms - a resource-poor country perspective
(Stellenbosch : Stellenbosch University, 2019-12)Background and objective: Hormonal therapy is the treatment of choice in most infants with infantile spasms (IS). Intramuscular adrenocorticotropic hormone (ACTH) has historically been the treatment of choice, ... -
An evaluation of fluid management strategies and outcomes for children with acute diarrhoea and dehydration admitted to a regional hospital in the Western Cape
(Stellenbosch : Stellenbosch University, 2021-12)Introduction Globally, acute diarrhoea remains one of the most common ailments in children. Despite the fluid management of diarrhoeal disease being based on relatively simple principles, many different clinical practice ... -
Factors predicting the long-term renal function in boys presenting with posterior urethral valves at Tygerberg Children's Hospital, South Africa : a ten year study
(Stellenbosch : Stellenbosch University, 2014-04)ENGLISH ABSTRACT: OBJECTIVES The aim of this study was to determine long-term renal function in boys presenting with posterior urethral valves at Tygerberg Children’s Hospital and to determine the prognostic value of ...