Browsing Doctoral Degrees (Psychiatry) by Title
Now showing items 1-20 of 39
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The adaptation and norming of selected psychometric tests for 12- to 15- year-old urbanized Western Cape adolescents
(Stellenbosch : Stellenbosch University, 2011-12)ENGLISH ABSTRACT: The practice of psychometric testing of cognitive functioning in South Africa is hampered by the paucity of normative data that adequately characterize our ethnically, linguistically, socioeconomically, ... -
An adapted intervention for problematic alcohol use in people living with AIDS and its impact on alcohol use, general functional ability, quality of life and adherence to HAART : a cluster randomized control trial at Opportunistic Infections Clinics in Zimbabwe
(Stellenbosch : Stellenbosch University, 2018-12)ENGLISH SUMMARY : With the advent of antiretroviral therapy, the HIV pandemic has become a chronic illness requiring lifelong treatment. The 90-90-90 strategy, adopted by UNAIDS, aims for (i) 90% of HIV infected persons ... -
Alcohol Induced Psychotic Disorder: a comparitive study in patients with alcohol dependance, schizophrenia and normal controls
(Stellenbosch : University of Stellenbosch, 2007-12)Alcohol-induced psychotic disorder (also known as alcohol hallucinosis) is a complication of alcohol abuse that requires clinical differentiation from alcohol withdrawal delirium and schizophrenia. Although extensively ... -
Association between motor timing and treatment outcomes in patients with alcohol and/or cocaine addiction in a rehabilitation programme
(Stellenbosch : Stellenbosch University, 2017-12)ENGLISH SUMMARY : Introduction: Motor timing deficits have been found in DA system related disorders and, more recently, also in individuals with Substance Use Disorders (SUD). Motor timing is fundamental to our ability ... -
Brain structural and white matter changes in first-episode schizophrenia and their demographic, clinical and cognitive correlates
(Stellenbosch : Stellenbosch University, 2018-03)ENGLISH SUMMARY : In schizophrenia, decreased brain volume and altered cortical thinning (especially in the frontal and temporal areas), as well as white matter deficits are described at the first-episode. The relationship ... -
Chromosomal aberrations in the Xhosa schizophrenia population
(Stellenbosch : Stellenbosch University, 2008-12)BACKGROUND: Schizophrenia is a heterogeneous illness resulting from complex gene-environment interplay. The majority of molecular genetic work done has involved Caucasian populations, with studies in these and Asian ... -
Cognitive training in patients with Trichotillomania (Hair-pulling Disorder)
(Stellenbosch : Stellenbosch University, 2019-04)ENGLISH SUMMARY : Background: Hair-pulling disorder (HPD), also known as trichotillomania, is a psychiatric condition characterized by recurrent pulling of hair, resulting in hair loss. Patients report repeated but ... -
The development and validation of the visual screening tool for anxiety disorders and depression in people living with hypertension and/or diabetes
(Stellenbosch : Stellenbosch University, 2018-12)ENGLISH SUMMARY : People living with hypertension and/or diabetes have an increased prevalence of depression and anxiety disorders. This contributes to functional limitations, poor quality of life, increased financial ... -
Efficacy and mechanism of action of intrahippocampalD-cycloserine in an animal model of Posttraumatic Stress Disorder (PTSD)
(Stellenbosch : Stellenbosch University, 2015-03)ENGLISH SUMMARY : Posttraumatic stress disorder (PTSD) has been described as a persistent (Bremner et al., 1996) and incapacitating (Zatzick et al., 1997; Mendlowicz &Stein 2000) psychiatric disorder which occurs after ... -
Epidemiological, phenomenological, and treatment aspects of trauma and posttraumatic stress disorder in children and adolescents
(Stellenbosch : University of Stellenbosch, 2005-12)Many gaps remain in our current state of knowledge about the epidemiology, phenomenology, neurobiology, and psychopharmacology of posttraumatic stress disorder (PTSD) in children and adolescents. Empirical evidence, ... -
Establishing modified mental health assertive treatment programs in a developing country
(Stellenbosch : Stellenbosch University, 2016-12)ENGLISH SUMMARY : An increasing demand for acute inpatient beds has put pressure on psychiatric services in the Western Cape Province of South Africa. While this is not unusual compared to elsewhere in the world, this ... -
Exploration of parental reflective function and mother-child interaction in a South African sample of women with peri- and postpartum psychosis
(Stellenbosch : Stellenbosch University, 2020-12)ENGLISH SUMMARY : Background: Severe mental illness in the peripartum period may exert a significant and detrimental impact on maternal caregiving and infant attachment. The experience of psychotic symptoms during pregnancy ... -
Hair cortisol as a neuroendocrine biomarker to evaluate the impact of chronic stress on the interaction between neuropsychiatric disorders and metabolic syndrome
(Stellenbosch : Stellenbosch University, 2020-03)ENGLISH SUMMARY : Individuals with neuropsychiatric disorders (NPDs) demonstrate increased rates of cardiovascular disease (CVD) and metabolic syndrome (MetS). There is evidence of dysregulated hypothalamic pituitary ... -
The identification of novel susceptibility genes involved in anxiety disorders
(Stellenbosch : Stellenbosch UniversityStellenbosch University, 2014-12)ENGLISH ABSTRACT: The etiology of anxiety disorders remains incompletely understood. Clear evidence for a genetic component has been proposed; however, there is also an increasing focus on environmental factors and the ... -
Implementation of international treatment guidelines in the treatment of schizophrenia : a study of the effects of an evidence-based seminar on the knowledge and treatment habits of a sample of international psychiatrists
(Stellenbosch : University of Stellenbosch, 2007-12)This study reports on the effect of seminar education by studying changes in knowledge, attitude and behaviour to haloperidol prescribing patterns of psychiatrists who In summary, this study demonstrated a direct relationship ... -
Integrating a trauma-informed psychological intervention for PTSD among PLWH on the Friendship Bench in Zimbabwe : a mixed methods formative study
(2018-12)ENGLISH SUMMARY : Introduction: Posttraumatic Stress Disorder (PTSD) and other Common Mental Disorders (CMD), such as depression and anxiety disorders, are highly prevalent in people living with HIV (PLWH). In Zimbabwe, ... -
Internalizing mental disorders in HIV : the role of environment, telomere length and selected genetic variants
(Stellenbosch : Stellenbosch University, 2020-03)ENGLISH SUMMARY : Background: HIV+ children and adolescents (CA-HIV) suffer from a considerable burden of internalizing mental disorders (IMDs), which are associated with negative outcomes, such as poor academic functioning ... -
Investigating the molecular aetiology of Obsessive-compulsive disorder (OCD) and clinically-defined subsets of OCD
(Stellenbosch : Stellenbosch University, 2006-03)ENGLISH ABSTRACT: Obsessive-compulsive disorder (OCD), a debilitating psychiatric disorder, affects 2-3% of the general population, and represents a global health problem. Evidence from family studies suggests that ... -
An investigation of the relationship between PTSD, reflective functioning and caregiving sensitivity amongst mothers misusing substances
(Stellenbosch : Stellenbosch University, 2020-03)ENGLISH SUMMARY : Substance use has increased significantly in South Africa and has been associated with several risk factors for both maternal and infant mental health including dysfunctional parenting practices. Trauma ... -
Limiting clinical heterogeneity in schizophrenia : can affected Xhosa sib pairs provide valid subtypes?
(Stellenbosch : University of Stellenbosch, 2005-12)BACKGROUND Schizophrenia is a heterogeneous disorder, which has been shown to have both environmental and genetic risk factors. Since family history (genetic loading) of psychosis appears to be one of the strongest risk ...
