Now showing items 1-2 of 2
The effects of acute hypoxia on metabolic enzymes in skeletal muscle
(Stellenbosch : University of Stellenbosch, 2006-03)
The responses of central systems to oxygen deprivation have been well characterised while adaptations in peripheral systems, such as skeletal muscles, have presented confounding variations. Several reasons for these ...
Acute simulated hypoxia and ischemia in cultured C2C12 myotubes : decreased phosphatidylinositol 3-kinase (PI3K)/Akt activity and its consequences for cell survival
(Stellenbosch : Stellenbosch University, 2008-12)
Cells are equipped with an array of adaptive mechanisms to contest the undesirable effects of ischemia and the associated hypoxia. Indeed, many studies have suggested that there is an increase in the PI3K/Akt pathway ...