Browsing Masters Degrees (Clinical Pharmacology) by Title
Now showing items 23-28 of 28
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The role of Phosphodiesterase (PDE3) in heart protection.
(Stellenbosch : Stellenbosch University, 2016-03)ENGLISH ABSTRACT: Introduction: During a heart attack the blood supply to the heart is reduced significantly, known as ischemia (Reimer & Jennings, 1991). Energy generating pathways that require oxygen become inhibited in ... -
The role of surfactant in, and a comparison of, the permeability of porcine and human epithelia to various chemical compounds
(Stellenbosch : University of Stellenbosch, 2005-12)In this thesis, research results are reported on the role of natural and synthetic surfactants on the in vitro permeability characteristics of various chemical compounds across porcine (buccal, bronchial, arterial, venous ... -
The specific binding of the thyroid hormones to matrix isolated from rat liver nuclei
(Health & Medical Publishing Group, 1982)Specific binding sites for the thyroid hormones have been demonstrated in the liver nuclear matrix, a structural framework of the nucleus. When labelled 3,5,3'-tri-iodo-L-thyronine ([125I]T3) is injected into rats, 5% of ... -
Using STORM and TIRF in tandem to investigate adherence and migration patterns in stem cells
(Stellenbosch : Stellenbosch University, 2021-03)Background: Cell migration is a dynamic process in physiology requiring pseudopodia, elongated cell protrusions, to associate with the extracellular matrix (ECM) and propel cells forward. The interaction is established ... -
Venomous spider bites in south africa: epidemiology and clinical features
(Stellenbosch : Stellenbosch University, 2019-04)Introduction: Worldwide the number of spider bite calls to poison centres comprises less than 2.5% of calls. Only a small proportion of spiders cause serious envenomation in humans. The known medically important spiders ... -
A zebrafish larval model for drug-induced hepatic Injury due to first-line antituberculosis drugs and possible prevention/treatment with N-acetyl-cysteine
(Stellenbosch : Stellenbosch University, 2022-11)ENGLISH ABSTRACT: Background Tuberculosis (TB) is ranked as the second most deadly infectious disease worldwide. First-line TB medication is associated with the development of drug-induced liver injury (DILI). The ...
