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High temperature multidimensional chromatography of complex and functionalized polyolefins
(Stellenbosch : Stellenbosch University, 2018., 2018-12)
ENGLISH ABSTRACT: Polyolefins like all other synthetic polymers have complex microstructures that must be understood in order to predict product performance and adjust catalyst and reactor technologies. Between synthesis ...
Using scalls to study the thermal behavior of polymers in solution
(Stellenbosch : Stellenbosch University, 2015-04)
ENGLISH ABSTRACT: This study involves the analysis of crystallization and melting behavior of polymers in solution,
using Solution crystallization by laser light scattering (Scalls) as analytical tool. Various other
techniques ...
Design and development of novel irreversible GSK-3β inhibitors to address Alzheimer's disease
(Stellenbosch : Stellenbosch University, 2018-03)
ENGLISH ABSTRACT: Molecular modelling on the GSK-3β protein was carried out to identify a library of suitable
electrophilic warhead containing ligands that have the necessary interactions with the binding
site. Several ...
Design and Synthesis of potent benzimidazolone HIV Non-nucleoside reverse transcriptase inhibitors
(Stellenbosch : Stellenbosch University, 2018-12)
ENGLISH ABSTRACT: Since the 1980’s, HIV has plagued the population on a global scale, with millions of newly infected
individuals reported every year. However, with the introduction of combination therapy, which ...
Experimental and computational approaches to investigate the high oxidation state oxo- and hydroxido- redox chemistry of osmium
(Stellenbosch : Stellenbosch University, 2016-03)
ENGLISH ABSTRACT: The OsVIII oxo/hydroxido complexes that are abundant in mild to relatively concentrated basic aqueous solutions are OsVIIIO4, [OsVIIIO4(OH)]- and two cis-[OsVIIIO4(OH)2]2- species. OsVIII complexes that ...
Rationalising the solid-state properties of dithiadiazolyl radicals using a combined theoretical and experimental approach
(Stellenbosch : Stellenbosch University, 2018-03)
ENGLISH ABSTRACT: The work describes a series of theoretical and experimental studies carried out to better understand the solid-state properties of 1,2,3,5-dithiadiazolyl (DTDA) radicals.
The attempted co-crystallisation ...