• Login
    Browsing Doctoral Degrees (Molecular Biology and Human Genetics) by Title 
    •   SUNScholar
    • Faculty of Medicine and Health Sciences
    • Department of Biomedical Sciences
    • Molecular Biology and Human Genetics
    • Doctoral Degrees (Molecular Biology and Human Genetics)
    • Browsing Doctoral Degrees (Molecular Biology and Human Genetics) by Title
    •   SUNScholar
    • Faculty of Medicine and Health Sciences
    • Department of Biomedical Sciences
    • Molecular Biology and Human Genetics
    • Doctoral Degrees (Molecular Biology and Human Genetics)
    • Browsing Doctoral Degrees (Molecular Biology and Human Genetics) by Title
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browsing Doctoral Degrees (Molecular Biology and Human Genetics) by Title

    • 0-9
    • A
    • B
    • C
    • D
    • E
    • F
    • G
    • H
    • I
    • J
    • K
    • L
    • M
    • N
    • O
    • P
    • Q
    • R
    • S
    • T
    • U
    • V
    • W
    • X
    • Y
    • Z

    Sort by:

    Order:

    Results:

    Now showing items 1-20 of 99

    • title
    • issue date
    • submit date
    • xmlui.ArtifactBrowser.ConfigurableBrowse.sort_by.datecreated
    • ascending
    • descending
    • 5
    • 10
    • 20
    • 40
    • 60
    • 80
    • 100
      • Thumbnail

        2020-12-11 Global transcriptomic investigation of the human macrophage response towards pathogenic/non-pathogenic mycobacteria 

        Mishra, Abhilasha Madhvi (Stellenbosch : Stellenbosch University, 2019-12)
        Background:Tuberculosis (TB) is a major cause of infection-related mortalityworldwide. In 2017 an estimated 1.3 million people who were HIV-negative died of TB. An estimated 5-10% of infected individual develop active ...
      • Thumbnail

        Analysis and application of evolutionary markers in the epidemiology of Mycobacterium tuberculosis 

        Van der Spuy, Gian Dreyer (Stellenbosch : Stellenbosch University, 2008-12)
        This series of studies includes both methodological analyses, aimed at furthering our understanding of, and improving the tools used in molecular epidemiology, and investigative projects which have used these tools to add ...
      • Thumbnail

        Analysis of copy number variation and disease mechanisms underlying Parkinson’s disease 

        Van der Merwe, Celia (Stellenbosch : Stellenbosch University, 2016-03)
        ENGLISH ABSTRACT : Parkinson’s disease (PD) is a neurodegenerative movement disorder characterized by the loss of dopaminergic neurons in the substantia nigra of the midbrain. Although the aetiology of PD is still not fully ...
      • Thumbnail

        Analysis of host determining factors in susceptibility to tuberculosis in the South African coloured population 

        De Wit, Erika (Stellenbosch : University of Stellenbosch, 2009-12)
        ENGLISH ABSTRACT: The infectious disease tuberculosis (TB) still represents a global threat due to its devastating effect on health and the subsequent high mortality rate. Previous studies have indicated that host genetic ...
      • Thumbnail

        Application of spoligotyping in the understanding of the dynamics of Mycobacterium tuberculosis strains in high incidence communities 

        Streicher, Elizabeth Maria (University of Stellenbosch. Faculty of Health Sciences. Dept. of Biomedical Sciences., 2007-03)
        Tuberculosis (TB) is a global health problem and demands rigorous control management efforts. A dramatic increase in the acquisition and spread of drug resistant TB globally has been observed in recent years. A grim picture ...
      • Thumbnail

        Aspects on advanced procedures during endoscopic retrograde cholangiopancreatography for complex hepatobiliary disorders 

        Lubbe, Jeanne Adele (Stellenbosch : Stellenbosch University, 2021-03)
        Background: The rapid development in endoscopic technology and associated skills has led to an increase in more advanced procedures being performed during endoscopic retrograde cholangiopancreatography (ERCP). Knowledge ...
      • Thumbnail

        A candidate and novel gene search to identify the PFHBII-causative gene 

        Fernandez, Pedro (Stellenbosch : Stellenbosch University, 2004-12)
        ENGLISH ABSTRACT: Heart failure due to cardiomyopathy or cardiac conduction disease is a major cause of mortality and morbidity in both developed and developing countries. Although defined as separate clinical entities, ...
      • Thumbnail

        A candidate and novel gene search to identify the PFHBII-causative gene 

        Fernandez, Pedro (Pedro Wallace) (Stellenbosch : University of Stellenbosch, 2004-12)
        ENGLISH ABSTRACT: Heart failure due to cardiomyopathy or cardiac conduction disease is a major cause of mortality and morbidity in both developed and developing countries. Although defined as separate clinical entities, ...
      • Thumbnail

        The characterisation of N-Acetyltransferase (NAT) in Mycobacterium tuberculosis 

        Sholto-Douglas-Vernon, Carolyn (Stellenbosch : University of Stellenbosch, 2005-03)
        ENGLISH ABSTRACT: A gene coding for Arylaminie N-acetyltransferase (NAT) has been found in Mycobacterium tuberculosis, the casual agent of tuberculosis (TB). N-acetyltransferase acetylates and inactivates isoniazid (INH), ...
      • Thumbnail

        Characterization of the innate and adaptive immune systems during active TB disease and during treatment 

        Kotze, Leigh Ann (Stellenbosch : Stellenbosch University, 2019-04)
        ENGLISH ABSTRACT: Individuals presenting with symptoms of active tuberculosis (TB) disease currently undergo a lengthy diagnostic procedure, followed by an intense six-month treatment regimen. Delays in accurate diagnoses ...
      • Thumbnail

        Characterization of the interaction between acetylcholinesterase and laminin : a template for discovering redundancy 

        Swart, Chrisna (Stellenbosch : Stellenbosch University, 2012-03)
        ENGLISH ABSTRACT: Apart from its primary function in the synaptic hydrolysis of acetylcholine, acetylcholinesterase (AChE) has been shown through in vitro demonstrations to be able to promote various non-cholinergic ...
      • Thumbnail

        Clinical and laboratory investigation of latex allergy in healthcare workers 

        De Beer, Corena (Stellenbosch : Stellenbosch University, 2004-12)
        ENGLISH ABSTRACT: Healthcare workers (HCWs) wear latex gloves to protect themselves and their patients against the transmission of microbial, viral and bloodborne diseases. These individuals are primarily exposed to ...
      • Thumbnail

        Clinically relevant mutations contributing to drug resistance in Mycobacterium tuberculosis 

        Du Plessis, Juanelle (Stellenbosch : Stellenbosch University, 2017-12)
        ENGLISH ABSTRACT: Single nucleotide variants are the underlying driver of drug resistance, strain fitness and adaptation in Mycobacterium tuberculosis and investigating the mechanistic and physiological aspects of these ...
      • Thumbnail

        Combining different types of highly parallelised technology datasets for bioinformatic analysis in the context of biomarker discovery for tuberculosis disease and treatment response 

        Maasdorp, Elizna (Stellenbosch : Stellenbosch University, 2021-12)
        Background: Monitoring of tuberculosis (TB) treatment response currently relies on month 2 sputum culture. It is a poor predictor of ultimate treatment failure and recurrent disease and has a long turnaround time of up ...
      • Thumbnail

        Combining different types of highly parallelised technology datasets for bioinformatic analysis in the context of biomarker discovery for tuberculosis disease and treatment response 

        Maasdorp, Elizna (Stellenbosch : Stellenbosch University, 2021-03)
        Background: Monitoring of tuberculosis (TB) treatment response currently relies on month 2 sputum culture. It is a poor predictor of ultimate treatment failure and recurrent disease and has a long turnaround time of up ...
      • Thumbnail

        Deciphering the physiology of drug tolerant and resistant Mycobacterium tuberculosis 

        Pule, Caroline (Stellenbosch : Stellenbosch University, 2021-03)
        ENGLISH ABSTRACT: Poor adherence to treatment for tuberculosis (TB) disease and the rising incidents of drug resistant Mycobacterium tuberculosis strains are factors that negatively influence TB control. The current study ...
      • Thumbnail

        Detection and Characterization of Mycobacterial Infections Occurring in Phacochoerus africanus (Gmelin, 1788) (Common Warthog) 

        Roos, Eduard Otto (Stellenbosch : Stellenbosch University, 2018-12)
        ENGLISH ABSTRACT: Mycobacterium bovis, a member of the Mycobacterium tuberculosis complex and the cause of bovine tuberculosis (bTB), has an extensive host range that includes livestock and wildlife. While warthogs are ...
      • Thumbnail

        The development of a novel fluorescentmarker phage technology system for the early diagnosis of tuberculosis disease 

        Van der Merwe, Ruben Gerhard (Stellenbosch : Stellenbosch University, 2012-12)
        ENGLISH ABSTRACT: Mycobacterium tuberculosis, the causative organism of tuberculosis (TB), is a major cause for mortality and morbidity world-wide with a death toll only second to HIV among infectious diseases. Drug ...
      • Thumbnail

        Development of immune-based TB tests suitable for resource limited settings 

        Essone Ndong, Paulin (Stellenbosch : Stellenbosch University, 2014-12)
        ENGLISH ABSTRACT: - Background - Tuberculosis (TB) is still one of the leading causes of death in poor socio-economic settings. This situation is encouraged by the lack of simple and rapid tests suitable for rapid ...
      • Thumbnail

        Diagnostic utility of the line probe assay for the detection of drug resistance in Mycobacterium tuberculosis 

        Barnard, Marinus (Stellenbosch : Stellenbosch University, 2013-03)
        ENGLISH ABSTRACT: The epidemic levels of drug-resistant tuberculosis (DR-TB) in high-burden countries such as South Africa, which is currently ranked as third highest in the world, is the result of a synergistic relationship ...

        Browse

        All of SUNScholarCommunities & CollectionsBy TitleBy AuthorBy AdvisorBy DateBy SubjectBy TypeThis CollectionBy TitleBy AuthorBy AdvisorBy DateBy SubjectBy Type

        My Account

        LoginRegister
        Copyright © Stellenbosch University | ISSN-L 2310-7855
        Contact Us