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Effect of an obesogenic diet on the epigenetic profile of livers from Wistar rats and treatment with an aspalathin-rich rooibos extract
(Stellenbosch : Stellenbosch University, 2021-12)Background There is a scarcity of knowledge about obesity and metabolic syndrome development and progression in females, who are often under-represented in preclinical research. The aims of this study were thus to ... -
Characterisation of high fat, high sugar diet-induced epigenetic changes in skeletal muscle of wistar rats and metabolic effects of an aspalathin-rich rooibos extract
(Stellenbosch : Stellenbosch University, 2021-12)Background Animal models are widely used to elucidate the pathophysiological mechanisms that underlie obesity and to test the efficacy of anti-obesity therapeutics. However, these models have been largely biased towards ...