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The impact of activation of the renin-angiotensin system in the development of insulin resistance in experimental models of obesity
(Stellenbosch : University of Stellenbosch, 2009-03)
Insulin stimulates the production of nitric oxide (NO) in endothelial cells and cardiac
myocytes by a signalling pathway that involves the insulin receptor substrate (IRS)-1,
phosphatidylinositol-3-kinase and protein ...
Measurement of free radicals and their effects on human spermatozoa
(Stellenbosch : University of Stellenbosch, 2006-03)
In this study, we presented data on the role of free radicals in human spermatozoa, particularly in the context of centrifugation and the potential development of defective sperm function. In order to achieve this, methods ...
The effects of physical and psychological stress on the behaviour and neurochemistry of rats
(Stellenbosch : University of Stellenbosch, 2005-12)
Stress is considered one of the major factors involved in the pathogenesis of affective disorders, for example, direct and indirect exposure to terrorist attacks or being subjected to subtle victimization. There is a long ...
Acrosome size and kinematics of human spermatozoa
(Stellenbosch : University of Stellenbosch, 2007-03)
For spermatozoa to gain access to the oocyte for fertilization, lytic enzymes need to
be released during the acrosome reaction. These enzymes, which are stored and
transported within an organelle termed the acrosome, ...