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A comparison of motility and head morphology of sperm using different semen processing methods and three different staining techniques
(Stellenbosch : University of Stellenbosch, 2010-12)
ENGLISH ABSTRACT: Sperm morphology remains an important parameter in the prediction of fertility, both
in vivo and in vitro. However, there remains a considerable level of concern
surrounding the true potential of this ...
A pathologic role for angiotensin II and endothelin-1 in cardiac remodelling and ischaemia and reperfusion injury in a rat model of the metabolic syndrome
(Stellenbosch : University of Stellenbosch, 2006-03)
Introduction: Obesity, which is implicated in the development of the metabolic
syndrome (MS) is reaching epidemic proportions worldwide. MS significantly
increases the risk of developing cardiovascular disease, which ...
Proteomic analysis of human sperm proteins in relation to sperm motility, morphology and energy metabolism
(Stellenbosch : University of Stellenbosch, 2010-12)
ENGLISH ABSTRACT: Male infertility is often associated with impaired sperm motility and morphology
(asthenoteratozoospermia) for which there is no specific therapeutic treatment. It has
come to light that the modification ...
Violence against women : impact on reproductive health and pregnancy outcome
(Stellenbosch : Stellenbosch University, 2003-03)
ENGLISH ABSTRACT: Introduction
Worldwide, up to 25% of women are assaulted during pregnancy, with estimates
varying between populations. Violence has been associated with adverse
pregnancy outcome, including preterm ...
Investigating the effects of nicotine on the male reproductive system
(Stellenbosch : Stellenbosch University, 2013-12)
ENGLISH ABSTRACT: Much has been documented about the detrimental effects of adverse lifestyle factor
exposure on the body. Exposure to factors, such as cigarette smoke, have proved to not
only be a burden on global health ...
The effect of hypoxia on nitric oxide and endothelial nitric oxide synthase in the whole heart and isolated cardiac cells: the role of the PI3–K / PKB pathway as a possible mediator.
(Stellenbosch : University of Stellenbosch, 2009-03)
In the heart, endothelial nitric oxide synthase (eNOS) is regarded as the most
important constitutively expressed enzymatic source of nitric oxide (NO), a
major cardiac signalling molecule. On the whole, NO is regarded ...
Gender selection: separation techniques for X- and Y-chromosome bearing human spermatozoa
(Stellenbosch : Stellenbosch University, 2013-12)
ENGLISH ABSTRACT: Preconceptual sex selection is an ethically justifiable process whereby X- and Y-chromosome bearing spermatozoa are isolated prior to fertilization of the oocyte in order to generate either a male or a ...
The role of glycogen synthase kinase-3 (GSK-3) protein in the development of myocardial hypertrophy in a rat model of diet induced obesity and insulin resistance
(Stellenbosch : Stellenbosch University, 2012-03)
ENGLISH ABSTRACT: Introduction: The worldwide escalation in the incidence of obesity and its strong association
with insulin resistance, type 2 diabetes and the cardiovascular complications that accompany
these disease ...
The effect of CPT-1 inhibition on myocardial function and resistance to ischemia/reperfusion injury in a rodent model of the metabolic syndrome
(Stellenbosch : University of Stellenbosch, 2010-12)
ENGLISH ABSTRACT: Background: Obesity is associated with dyslipidemia, insulin resistance and glucose intolerance and together these components characterise the metabolic syndrome (Dandona et al. 2005). In the state of ...
Nitric oxide and the endothelium : characterisation of in vitro nitric oxide detection techniques and an ex vivo method of measuring endothelial function
(Stellenbosch : Stellenbosch University, 2014-04)
ENGLISH ABSTRACT: Introduction: Nitric oxide (NO) is an important chemical messenger in the cardiovascular
system. Despite considerable progress in this field, there remains an on-going need for
affordable and user-friendly ...