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The effects of chronic melatonin treatment on myocardial function and ischaemia and reperfusion injury in a rat model of diet-induced obesity
(Stellenbosch : Stellenbosch University, 2010-03)
ENGLISH ABSTRACT: Obesity is a major risk factor for ischaemic heart disease. Obesity-induced metabolic
abnormalities have been associated with increased oxidative stress which may play an
important role in the increased ...
A comparison of motility and head morphology of sperm using different semen processing methods and three different staining techniques
(Stellenbosch : University of Stellenbosch, 2010-12)
ENGLISH ABSTRACT: Sperm morphology remains an important parameter in the prediction of fertility, both
in vivo and in vitro. However, there remains a considerable level of concern
surrounding the true potential of this ...
The efficacy of Diavite tm (Prosopis glandulosa) as anti-diabetic treatment in rat models of streptozotocin-induced type 1 diabetes and diet-induced-obese insulin resistance
(Stellenbosch : University of Stellenbosch, 2010-03)
ENGLISH ABSTRACT: Introduction: Obesity and its associated complications, such as the metabolic syndrome, hypertension and cardiovascular disease, are escalating worldwide. In recognition of this, untested remedies advertised ...
A pathologic role for angiotensin II and endothelin-1 in cardiac remodelling and ischaemia and reperfusion injury in a rat model of the metabolic syndrome
(Stellenbosch : University of Stellenbosch, 2006-03)
Introduction: Obesity, which is implicated in the development of the metabolic
syndrome (MS) is reaching epidemic proportions worldwide. MS significantly
increases the risk of developing cardiovascular disease, which ...
Proteomic analysis of human sperm proteins in relation to sperm motility, morphology and energy metabolism
(Stellenbosch : University of Stellenbosch, 2010-12)
ENGLISH ABSTRACT: Male infertility is often associated with impaired sperm motility and morphology
(asthenoteratozoospermia) for which there is no specific therapeutic treatment. It has
come to light that the modification ...
Violence against women : impact on reproductive health and pregnancy outcome
(Stellenbosch : Stellenbosch University, 2003-03)
ENGLISH ABSTRACT: Introduction
Worldwide, up to 25% of women are assaulted during pregnancy, with estimates
varying between populations. Violence has been associated with adverse
pregnancy outcome, including preterm ...
Investigating the effects of nicotine on the male reproductive system
(Stellenbosch : Stellenbosch University, 2013-12)
ENGLISH ABSTRACT: Much has been documented about the detrimental effects of adverse lifestyle factor
exposure on the body. Exposure to factors, such as cigarette smoke, have proved to not
only be a burden on global health ...
The effect of hypoxia on nitric oxide and endothelial nitric oxide synthase in the whole heart and isolated cardiac cells: the role of the PI3–K / PKB pathway as a possible mediator.
(Stellenbosch : University of Stellenbosch, 2009-03)
In the heart, endothelial nitric oxide synthase (eNOS) is regarded as the most
important constitutively expressed enzymatic source of nitric oxide (NO), a
major cardiac signalling molecule. On the whole, NO is regarded ...
Gender selection: separation techniques for X- and Y-chromosome bearing human spermatozoa
(Stellenbosch : Stellenbosch University, 2013-12)
ENGLISH ABSTRACT: Preconceptual sex selection is an ethically justifiable process whereby X- and Y-chromosome bearing spermatozoa are isolated prior to fertilization of the oocyte in order to generate either a male or a ...
The role of glycogen synthase kinase-3 (GSK-3) protein in the development of myocardial hypertrophy in a rat model of diet induced obesity and insulin resistance
(Stellenbosch : Stellenbosch University, 2012-03)
ENGLISH ABSTRACT: Introduction: The worldwide escalation in the incidence of obesity and its strong association
with insulin resistance, type 2 diabetes and the cardiovascular complications that accompany
these disease ...