Search
Now showing items 1-7 of 7
Effect of melatonin on myocardial susceptibility to ischaemia and reperfusion damage in a rat model of high-fat diet-induced obesity
(Stellenbosch : Stellenbosch University, 2015-12)
ENGLISH ABSTRACT: Obesity has reached epidemic proportions worldwide and is currently a serious health problem.
It is associated with metabolic abnormalities, oxidative stress, hypertension, insulin resistance
and an ...
A pathologic role for angiotensin II and endothelin-1 in cardiac remodelling and ischaemia and reperfusion injury in a rat model of the metabolic syndrome
(Stellenbosch : University of Stellenbosch, 2006-03)
Introduction: Obesity, which is implicated in the development of the metabolic
syndrome (MS) is reaching epidemic proportions worldwide. MS significantly
increases the risk of developing cardiovascular disease, which ...
The effects of physical and psychological stress on the behaviour and neurochemistry of rats
(Stellenbosch : University of Stellenbosch, 2005-12)
Stress is considered one of the major factors involved in the pathogenesis of affective disorders, for example, direct and indirect exposure to terrorist attacks or being subjected to subtle victimization. There is a long ...
Optimization of experimental conditions and analysis tools for the study of phosphodiesterase-5 in a model of cultured adult rat cardiomyocytes
(Stellenbosch : Stellenbosch University, 2017-03)
ENGLISH ABSTRACT : Part 1
Introduction: Phosphodiesterases (PDEs) hydrolyse cyclic nucleotides that regulate ischemia-reperfusion injury (IRI) in the heart. Phosphodiesterases-5 (PDE5) inhibition increases cyclic guanosine ...
The role of mitophagy in damage incurred by ischaemia/reperfusion
(Stellenbosch : Stellenbosch University, 2017-03)
ENGLISH ABSTRACT : Background and aims: Mitophagy is a specialised process of autophagy whereby dysfunctional mitochondria are removed. Mitophagy has been increasingly recognised as an essential process to sustain a healthy ...
The treatment effect of Rooibos on vascular function and signalling pathways of aortas from diet induced obese rats.
(Stellenbosch : Stellenbosch University, 2017-03)
ENGLISH ABSTRACT :
Introduction:
Obesity is becoming a worldwide health problem and is a well-documented independent risk factor for the development of endothelial dysfunction (decreased nitric oxide (NO) bioavailability) ...
Effect of Aspalathus linearis supplementation, during anti-retroviral treatment, on the heart and aortas of male Wistar rats and the effects of drinking rooibos on the cardiovascular profile of patients on ART.
(Stellenbosch : Stellenbosch University, 2017-03)
ENGLISH ABSTRACT :
Introduction
Improved survival rates in the human immunodeficiency virus (HIV) population, due to the use of
antiretroviral therapy (ART), are associated with increased risk for cardiovascular disease ...